The luminal membrane of rat thick limb expresses AT1 receptor and aminopeptidase activities

Kidney International

Volumn 62, Issue 2, 2002, Pages 434-445

  Poumarat, Jean Stéphane ^a,b,c,d   Houillier, Pascal ^a,b,c,d   Rismondo, Claude ^a,b,c,d   Roques, Bernard ^a,b,c,d   Lazar, George ^a,b,c,d   Paillard, Michel ^a,b,c,d   Blanchard, Anne ^a,b,c,d  

^a SORBONNE UNIVERSITÉ   (France)

^b INSERM   (France)

^c HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^d CNRS   (France)

Author keywords

Aminopeptidases A and N; Angiotensin II; AT1 receptor; Extracellular fluid; Kidney; Sodium chloride handling; Thick ascending limb

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN RECEPTOR; ANTIBODY; CALCIUM ION; FURA 2; GLUTAMYL AMINOPEPTIDASE; IODINE 125; ISOLEUCINE; MICROSOMAL AMINOPEPTIDASE; SODIUM CHLORIDE; AMINOPEPTIDASE; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; ANGIOTENSIN II [1 SARCOSINE 8 ISOLEUCINE]; CALCIUM; DIAGNOSTIC AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; RADIOACTIVE IODINE;

ABSORPTION; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; BASOLATERAL MEMBRANE; BINDING AFFINITY; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; HENLE LOOP; IMMUNOBLOTTING; IN VITRO STUDY; ISOLATION PROCEDURE; LIMB; MALE; MEMBRANE BIOLOGY; MEMBRANE VESICLE; MICROFLUOROMETRY; MONITORING; NONHUMAN; PERFUSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SIGNAL TRANSDUCTION; STAINING; ANIMAL; CELL MEMBRANE; CELL POLARITY; DRUG EFFECT; ENZYMOLOGY; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

1-SARCOSINE-8-ISOLEUCINE ANGIOTENSIN II; AMINOPEPTIDASES; ANGIOTENSIN II; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; ANTIBODY SPECIFICITY; ANTIGENS, CD13; CALCIUM; CELL MEMBRANE; CELL POLARITY; GLUTAMYL AMINOPEPTIDASE; IODINE RADIOISOTOPES; LOOP OF HENLE; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTORS, ANGIOTENSIN; SODIUM CHLORIDE;

EID: 0035991415     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2002.00453.x     Document Type: Article

References (54)

1. Immunohistochemical localization of ANG II AT 1 receptor in adult rat kidney using a monoclonal antibody
2. Distribution of angiotensin AT 1 and AT2 receptor subtypes in the rat kidney
3. Tubular transport responses to angiotensin
4. Angiotensin II: A potent regulator of acidification in the rat early proximal convoluted tubule
5. Effect of Angiotensin II on ammonia production and secretion by mouse proximal tubules perfused in vitro
6. Concentrations and actions of intraluminal angiotensin II
7. Endogenous angiotensin concentrations in specific intrarenal fluid compartments of the rat
8. Endogenous production of angiotensin II modulates rat proximal tubule transport
9. Role of angiotensin II in glomerulotubular balance
10. Differential regulation of rat glomerular and proximal tubular renin mRNA following uninephrectomy
11. 1 receptor
12. Angiotensin II binding sites on isolated rat renal brush border membranes
13. Angiotensin II-binding sites in rat and primate isolated renal tubular basolateral membranes
14. Angiotensin II receptor subtypes in the kidney
15. Effects of angiotensin II and nonpeptide receptor antagonists on transduction pathways in rat proximal tubule
16. Polarized rabbit type 1 angiotensin II receptors manifest differential rates of endocytosis and recycling
17. 2
18. Angiotensin II directly increases rabbit renal brush-border membrane sodium transport: Presence of local signal transduction system
19. Angiotensin II binding sites in individual segments of the rat nephron
20. Expression of Type 1 angiotensin II receptor subtypes and angiotensin II-induced calcium mobilization along the rat nephron
21. - cotransport via 20-HETE and PKC in medullary thick ascending limb
22. + channel in the thick ascending limb of the rat kidney
23. i along the rat nephron
24. Immunoelectron microscopic demonstration of the membrane proteases aminopeptidase N/CD13 and dipeptidyl peptidase IV/CD 26 in normal and neoplastic renal parenchymal tissues and cells
25. 4-receptor system in the rat kidney
26. Isolation and characterization of luminal and basolateral plasma membrane vesicles from medullary thick ascending limb loop of Henle
27. Quick isolation of rat medullary thick ascending limbs. Enzymatic and metabolic characterization
28. + exchangers of thick ascending limbs of rat kidney: Evidence from isolated membranes
29. Water and solute permeabilities of medullary thick ascending limb apical and basolateral membranes
30. - exchangers of rat thick limbs
31. + exchanger isoform NHE4 in rat thick ascending limbs
32. Pantothenate-sodium cotransport in renal brush-border membranes
33. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
34. Differential inhibition of aminopeptidase A and aminopeptidase N by new beta-amino thiols
35. 3-Amino-2-tetralone derivatives: Novel potent and selective inhibitors of aminopeptidase-M (EC 3.4.11.2)
36. Inhibition of aminopeptidases N, A, and W. A re-evaluation of the actions of bestatin and inhibitors of angiotensin converting enzyme
37. Aminopeptidase A: Distribution in rat brain nuclei and increased activity in spontaneously hypertensive rats
38. 2+ indicators with greatly improved fluorescence properties
39. Discrimination of angiotensin II receptor subtypes by dithiothreitol
40. 2+, contributes to the substrate specificity of aminopeptidase A
41. A tyrosine residue essential for catalytic activity in aminopeptidase A
42. Inhibition of aminopeptidases by aminophosphonates
43. + transporters in the medullary thick ascending limb of the kidney: Molecular mechanisms, function and regulation
44. Angiotensin II receptor heterogeneity
45. + absorption via a cytochrome P-450-dependent pathway in MTAL
46. Glutamyl aminopeptidase (aminopeptidase A), the BP-1/6C3 antigen
47. Rat kidney glutamyl aminopeptidase (aminopeptidase A): Molecular identity and cellular localization
48. Aminopeptidase A: A nephritogenic target antigen of nephrotoxic serum
49. Study on asparagine 353 in aminopeptidase A: Characterization of a novel motif (GXMEN) implicated in exopeptidase specificity of monozinc aminopeptidases
50. Differences in the properties and enzymatic specificities of the two active sites of angiotensin I-converting enzyme (kininase II). Studies with bradykinin and other natural peptides
51. The origin of urinary angiotensins in humans
52. Intrarenal production of angiotensin II
53. 2
54. Cytoskeleton-dependent endocytosis is required for apical type 1 angiotensin II receptor-mediated phospholipase C activation in cultured rat proximal tubule cells