The anti-platelet agent, ticlopidine, upregulates interleukin-1-beta-stimulated nitric oxide production in cultured rat vascular smooth muscle cells

Experimental Nephrology

Volumn 10, Issue 4, 2002, Pages 267-274

  Inoue, Makoto ^a   Kusano, Eiji ^a   Ito, Chiharu ^a   Akimoto, Tetsu ^a   Iimura, Osamu ^a   Nemoto, Jun ^a   Amemiya, Morimasa ^a   Muto, Shigeaki ^a   Asano, Yasushi ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Anti platelet aggregation drug; Cyclic nucleotides; Inducible nitric oxide synthase; Interleukin 1 ; Nitric oxide; Ticlopidine; Vascular smooth muscle cells

Indexed keywords

ANTITHROMBOCYTIC AGENT; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE INHIBITOR; INTERLEUKIN 1BETA; ISOBUTYLMETHYLXANTHINE; ISOENZYME; KT 5720; KT 5823; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRITE; PHOSPHODIESTERASE INHIBITOR; TICLOPIDINE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1; NITRATE; NOS2 PROTEIN, RAT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CHEMICAL ANALYSIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; METABOLITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; RNA ANALYSIS; VASCULAR SMOOTH MUSCLE; ANIMAL; AORTA; CYTOLOGY; DRUG EFFECT; GENETICS; MALE; METABOLISM; SPRAGUE DAWLEY RAT; UPREGULATION;

ANIMALS; AORTA; CELLS, CULTURED; CYCLIC AMP; CYCLIC GMP; INTERLEUKIN-1; MALE; MUSCLE, SMOOTH, VASCULAR; NITRATES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; PHOSPHODIESTERASE INHIBITORS; PLATELET AGGREGATION INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TICLOPIDINE; UP-REGULATION;

EID: 0035991142     PISSN: 10187782     EISSN: None     Source Type: Journal    
DOI: 10.1159/000063701     Document Type: Article

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