Reverse transcriptase-polymerase chain reaction detection of circulating tumor cells in patients with melanoma: Correlation with clinical stage, tumor thickness and histological type

Pathology International

Volumn 52, Issue 4, 2002, Pages 294-299

  Carrillo, Esmeralda ^a   Prados, Jose ^b   Melguizo, Consolación ^b   Marchal, Juan Antonio ^a   Vélez, Celia ^b   Serrano, Salvio ^c   Boulaiz, Houria ^c   Mérida, Juan Antonio ^c   Aránega, Antonia ^c  

^a UNIVERSITY OF JAÉN   (Spain)

^b UNIVERSITY OF ALMERÍA   (Spain)

^c UNIVERSITY OF GRANADA   (Spain)

Author keywords

Circulating tumor cells; Melanoma patients; Metastatic disease; PCR; Tyrosinase mRNA

Indexed keywords

MONOPHENOL MONOOXYGENASE; RNA; MESSENGER RNA;

ADULT; AGED; ARTICLE; BLOOD; CANCER CELL; CANCER STAGING; CELL MIGRATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE MARKER; FEMALE; HISTOLOGY; HUMAN; MAJOR CLINICAL STUDY; MALE; MELANOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR VOLUME; ENZYMOLOGY; GENETICS; METABOLISM; METASTASIS; METHODOLOGY; MIDDLE AGED; PATHOLOGY; SEX DIFFERENCE; SKIN TUMOR; TUMOR EMBOLISM;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; HUMAN; MALE; MELANOMA; MIDDLE AGE; MONOPHENOL MONOOXYGENASE; NEOPLASM CIRCULATING CELLS; NEOPLASM STAGING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; SEX FACTORS; SKIN NEOPLASMS; SUPPORT, NON-U.S. GOV'T; HUMANS; MIDDLE AGED;

EID: 0035990890     PISSN: 13205463     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1827.2002.01344.x     Document Type: Article

References (30)

1. Thickness, cross-sectional areas and depth of invasion in the prognosis of cutaneous melanoma
2. The histogenesis and biologic behaviour of primary human malignant melanomas of the skin
3. Epidemiology of malignant melanoma in central Europe: Risk factors and prognostic predictors. Results of the Central Malignant Melanoma Registry of the German Dermatological Society
4. Polymerase chain reaction detection of circulating melanocytes as a prognostic marker in patients with melanoma
5. Multivariate analysis of the relationship between survival and the microstage of primary melanoma by Clark level and Breslow thickness
6. Detection of occult melanoma cells in blood with a multiple-marker polymerase chain reaction assay
7. Molecular detection and characterisation of circulating tumour cells and micrometastases in solid tumours
8. Detection of circulating tumor cells in men with localized prostate cancer
9. Sensitive detection of circulating hepatocellular carcinoma cells in peripheral venous blood
10. P-53 protein and Ki-67-antigen expression are both reliable biomarkers of prognosis in thick stage I nodular melanoma of the skin
11. Transcription of the MAGE-1 gene and the methylation status of its Ets binding promoter elements: A quantitative analysis in melanoma cell lines using a real-time polymerase chain reaction technique
12. Detection of melanoma cells in peripheral blood by means of reverse transcriptase and polymerase chain reaction
13. A polymerase chain reaction-based semiquantitave assessment of malignant melanoma cells in peripheral blood
14. Peripheral blood tyrosinase messenger RNA detection and survival in malignant melanoma
15. Evaluation of tyrosinase mRNA as a tumor marker in the blood of melanoma patients
16. Reliability of RT-PCR based assays for detection of circulating tumour cells. A quality-assurance initiative of the EORTC melanoma cooperative group
17. Detection of melanoma micrometastases in the sentinel lymph node and in nonsentinel nodes by tyrosinase polymerase chain reaction
18. Optimization of the tyrosinase mRNA probe to detect circulating melanocytes with reverse transcription and polymerase chain reaction
19. Hematogenous spread of malignant melanoma cells in different stages of disease
20. Detection of residual tumor cells in patients with malignant melanoma responding to immuno-therapy
21. Polymerase chain reaction-based detection of circulating melanoma cells as an effective marker of tumor progression
22. Detection of circulating melanoma cells by specific amplification of tyrosinase complementary DNA is no reliable tumor marker in melanoma patients
23. Prognostic significance of peripheral blood and bone marrow tyrosinase messenger RNA in malignant melanoma
24. Prognostic significance of the detection of circulating malignant cells by reverse transcriptase-polymerase chain reaction in long-term clinically disease-free melanoma patients
25. Polymerase chain reaction for detection of melanoma in peripheral blood. Too early to assess clinical value
26. Polymerase chain reaction detection of melanoma cells in the circulation. Relation to clinical stage surgical treatment and recurrence from melanoma
27. Detection of circulating neoplastic cells by RT-PCR in malignant melanoma. Correlation with clinical stage and prognosis
28. RT-PCR for tyrosinase-mRNA positive cells in peripheral blood: Evaluation strategy and correlation with known prognostic markers in 123 melanoma patients
29. The analysis of tyrosinase-specific mRNA in blood samples of melanoma patients by RT-PCR is not a useful test for metastatic tumor progression
30. A prognostic model for predicting 10 year survival in patients with primary melanoma