The expression of retinoic acid receptors and the effects in vitro by retinoids in human pancreatic cancer cell lines

Pancreas

Volumn 25, Issue 1, 2002, Pages 49-56

  Albrechtsson, Elin ^a   Ohlsson, Bodil ^a   Axelson, Jan ^a  

^a Department of Surgery ^*  (Sweden)

Author keywords

Cell lines; Cell proliferation; Pancreatic cancer; Retinoic acid; Retinoic acid receptors; Vitamin A

Indexed keywords

ALITRETINOIN; ISOTRETINOIN; RECEPTOR PROTEIN; RECEPTOR SUBTYPE; RETINOIC ACID RECEPTOR; RETINOID; RETINOID X RECEPTOR; ANTINEOPLASTIC AGENT; RETINOIC ACID; TRANSCRIPTION FACTOR;

ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; PANCREAS CANCER; PRIORITY JOURNAL; RECEPTOR INTRINSIC ACTIVITY; ADENOCARCINOMA; BIOSYNTHESIS; CELL CULTURE; CELL DIVISION; DOSE RESPONSE; METABOLISM; PANCREAS TUMOR; WESTERN BLOTTING;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CELL DIVISION; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMAN; IN VITRO; ISOTRETINOIN; PANCREATIC NEOPLASMS; RECEPTORS, RETINOIC ACID; SUPPORT, NON-U.S. GOV'T; TRANSCRIPTION FACTORS; TRETINOIN; TUMOR CELLS, CULTURED; HUMANS; RETINOID X RECEPTORS;

EID: 0035990286     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006676-200207000-00013     Document Type: Article

References (45)

1. Retinoic acid: Biochemistry, pharmacology, toxicology and therapeutic use
2. The retinoids: A review of their clinical, pharmacology and therapeutic use
3. Retinoids: An overview of pharmakinetics and therapeutic value
4. Use of all-trans-retinoic acid in the treatment of acute promyelocytic leukemia
5. All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results
6. A clinical and experimental study on all-trans retinoic acid-treated acute promyelocytic leukemia patients
7. Differentiation therapy of acute promyelocytic leukemia with tretinoin
8. 9-Cis-retinoic acid: Effects on normal and leukemic hematopoiesis in vitro
9. Cancer combination chemotherapy with retinoids: Experimental rationale
10. Effect of 9-cis-retinoic acid on growth and RXR expression in human breast cancer cells
11. Retinoic acid receptor α expression correlates with retinoid-induced growth inhibition of human breast cancer cells regardless of estrogen receptor status
12. The cytostatic effect of 9-cis-retinoic acid, tretinoin and isotretinoin on three different human bladder cancer cell lines in vitro
13. Comparison of low-dose isotretinoin with β-carotene to prevent oral carcinogenesis
14. Prevention of skin cancer in xeroderma pigmentosum with the use of oral isotretinoin
15. 13-Cis-retinoic acid and interferon α-2a: Effective combination therapy for advanced squamous cell carcinoma of the skin
16. 13-Cis-reinoic acid plus interferon α-2a: Highly active systemic therapy for squamous cell carcinoma of the cervix
17. Cancer chemotherapy by combination of retinoids with cytokines and vitamin D analogues: Experimental and clinical results
18. EB1089: A new vitamin D analog that inhibits the growth of breast cancer cells in vivo and in vitro
19. 3 analogues on HL-60 myeloid leukemic cells
20. Vitamin D analogs and retinoids exhibit additive cytotoxicity to human myeloma cell lines
21. Growth-inhibitory effects of vitamin D analogues and retinoids on human pancreatic cancer cells
22. Retinoic acid receptors and cellular retinoic binding proteins: Complex interplay in retinoic signalling
23. Vitamin A receptors
24. Multiplicity generates diversity in the retinoic acid pathway
25. Retinoic acid alters hindbrain Hox code and induces transformation of rhombomeres 2/3 into a 4/5 identity
26. Exogenous retinoic acid rapidly induces anterior ectopic expression of murine Hox-2 genes in vivo
27. Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid
28. Respecification of vertebral identities by retinoic acid
29. Sequential activation of Hox-2 homeobox genes by retinoic acid in human embryonal carcinoma cells
30. Differential regulation by retinoic acid of the homeobox genes of the four Hox loci in human embryonal carcinoma cells
31. Retinoic acid and its receptors
32. High frequency of retinoic acid receptor β abnormalities in human lung cancer
33. Tumor-suppressive effect of the retinoic acid receptor beta in human epidermoid lung cancer cells
34. An improved calorimetric assay for cell proliferation and viability using the tetrazolium salt XTT
35. Immunodetection of multiple species of retinoic acid receptor α: Evidence for phosphorylation
36. Retinoic acid receptor β regulates growth and differentiation in human pancreatic carcinoma cells
37. 1 expression determines retinoic sensitivity in pancreatic carcinoma cells
38. Retinoic acid receptor α mediates growth inhibition by retinoids in rat pancreatic carcinoma DSL-6A/C1 cells
39. Retinoids: Effects on growth, differentiation, and nuclear receptor expression in human pancreatic carcinoma cell lines
40. Differential growth regulation by all-trans-retinoic acid is determined by protein kinase C α in human pancreatic carcinoma cells
41. Differentiation of pancreatic carcinoma induced by retinoic acid or sodium butyrate: A morphologic and molecular analysis of four cell lines
42. Clinical pharmacology of oral alltrans retinoic acid in patients with acute promyelocytic leukemia
43. All-trans-retinoic acid inhibits growth of human pancreatic cancer cell lines
44. Differential and antagonistic effects of 9-cis-retinoic acid and vitamin D analogues on pancreatic cancer cells in vitro
45. Advanced carcinoma of the pancreas: Phase II study of combined chemotherapy, beta-interferon, and retinoids