Adverse pulmonary vascular effects of high dose tricyclic antidepressants: Acute and chronic animal studies

European Respiratory Journal

Volumn 20, Issue 2, 2002, Pages 344-352

  Liu, X ^a   Emery, C J ^a   Laude, E ^a   Herget, J ^a   Gill, G ^a   Cope, G ^a   Barer, G R ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Acute respiratory distress; Antidepressants; Endothelium; Lung; Pulmonary; Syndrome

Indexed keywords

AMITRIPTYLINE; CALCIUM CHANNEL BLOCKING AGENT; ENDOTHELIN CONVERTING ENZYME; HISTAMINE; IMIPRAMINE; IPRINDOLE; LIPOXYGENASE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE; NORADRENALIN; PROSTAGLANDIN SYNTHASE; SEROTONIN; SODIUM CHLORIDE; TRICYCLIC ANTIDEPRESSANT AGENT;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL RUPTURE; CAT; CONTROLLED STUDY; DRUG MEGADOSE; DRUG OVERDOSE; ENZYME ACTIVITY; HISTAMINE RELEASE; HYPOXIC LUNG VASOCONSTRICTION; ISOLATION PROCEDURE; LUNG ALVEOLUS EPITHELIUM; LUNG ARTERY PRESSURE; LUNG CAPILLARY; LUNG EDEMA; LUNG ENDOTHELIUM; MALE; NONHUMAN; NORADRENALIN RELEASE; ORGAN WEIGHT; PRESSOR RESPONSE; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RAT; SEROTONIN RELEASE; SEROTONIN UPTAKE; ACUTE DISEASE; ANIMAL; CHEMICALLY INDUCED DISORDER; CHRONIC DISEASE; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECT; INTOXICATION; LUNG DISEASE; PATHOLOGY; PATHOPHYSIOLOGY; PULMONARY ARTERY; VASCULAR DISEASE; WISTAR RAT;

ACUTE DISEASE; AMITRIPTYLINE; ANIMAL; ANTIDEPRESSIVE AGENTS, TRICYCLIC; CATS; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; IMIPRAMINE; IPRINDOLE; LUNG DISEASES; OVERDOSE; PULMONARY ARTERY; RATS; RATS, WISTAR; SUPPORT, NON-U.S. GOV'T; VASCULAR DISEASES; ANIMALS;

EID: 0035989818     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.02.00225402     Document Type: Article

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