Insulin-mediated tyrosine phosphorylation of myosin heavy chain and concomitant enhanced association of C-terminal Src kinase during skeletal muscle differentiation

Cell Biology International

Volumn 26, Issue 6, 2002, Pages 557-561

  Goel, Hira Lal ^a   Dey, Chinmoy Sankar ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Csk; Insulin; Myogenesis; Myosin heavy chain; Tyrosine phosphorylation

Indexed keywords

INSULIN; MYOSIN HEAVY CHAIN; PROTEIN TYROSINE KINASE; CBP PROTEIN, RAT; MEMBRANE PROTEIN; PHOSPHOPROTEIN; PROTEIN TYROSINE KINASE C SRC; PROTEIN-TYROSINE KINASE C-SRC; TYROSINE;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; IMMUNOPRECIPITATION; MUSCLE CELL; MUSCLE DEVELOPMENT; NONHUMAN; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; RAT; SKELETAL MUSCLE; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PRENATAL DEVELOPMENT; UPREGULATION;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; INSULIN; MEMBRANE PROTEINS; MUSCLE FIBERS; MUSCLE, SKELETAL; MYOSIN HEAVY CHAINS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; RATS; TYROSINE; UP-REGULATION;

EID: 0035989114     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1006/cbir.2002.0878     Document Type: Article

References (13)

1. C-terminal Src kinase associates with ligand-stimulated insulin-like growth factor-I receptor
2. Overexpressed Csk tyrosine kinase is localized in focal adhesions, causes reorganization of alpha v beta 5 integrin, and interferes with HeLa cell spreading
3. Maintenance of the differentiated state in skeletal muscle: Activation of v-Src disrupts sarcomeres in quail myotubes
4. Insulin produces myogenesis in C2C12 myoblasts by induction of NF-kappaB and downregulation of AP-1 activities
5. Chemoattractantmediated increases in cGMP induce changes in Dictyostelium myosin II heavy chain-specific protein kinase C activities
6. Assemblydependent phosphorylation of myosin and paramyosin of native thick filaments in Caenorhabditis elegans
7. Myosin light chain kinase and myosin light chain phosphatase from Dictyostelium: Effects of reversible phosphorylation on myosin structure and function
8. Effect of heavy chain phosphorylation on the polymerization and structure of Dictyostelium myosin filaments
9. Intermolecular versus intramolecular interactions of Dictyostelium myosin: Possible regulation by heavy chain phosphorylation
10. A role for the actin cytoskeleton in the hormonal and growth-factormediated activation of protein kinase B
11. Measurement of protein using bicinchoninic acid
12. Actin filaments facilitate insulin activation of the src and collagen homologous/mitogen-activated protein kinase pathway leading to DNA synthesis and c-fos expression
13. The insulin signaling system