Effect of coincident enterovirus infection and cows' milk exposure on immunisation to insulin in early infancy

Diabetologia

Volumn 45, Issue 4, 2002, Pages 531-534

  Vaarala, O ^a   Klemetti, P ^a   Juhela, S ^a   Simell, O ^b   Hyoty H ^c   Ilonen, J ^b  

^a NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

^c TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

Bovine insulin; Cows' milk; Coxsackievirus; Dietary antigen; Enterovirus; Oral tolerance

Indexed keywords

AUTOANTIBODY; BOVINE INSULIN; HLA DQ ANTIGEN; IMMUNOGLOBULIN G ANTIBODY; VIRUS ANTIGEN; IMMUNOGLOBULIN G; INSULIN ANTIBODY;

ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; COXSACKIE VIRUS B4; ENTEROVIRUS INFECTION; ENZYME IMMUNOASSAY; FEMALE; GENOTYPE; HUMAN; IMMUNE RESPONSE; IMMUNIZATION; INFANT; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE PROLIFERATION; MAJOR CLINICAL STUDY; MALE; MILK; PRIORITY JOURNAL; RISK FACTOR; VIRUS REPLICATION; ANIMAL; BABY FOOD; BLOOD; CATTLE; COHORT ANALYSIS; ENTEROVIRUS; FOLLOW UP; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; T LYMPHOCYTE;

ANIMAL; AUTOANTIBODIES; CATTLE; COHORT STUDIES; ENTEROVIRUS B, HUMAN; ENTEROVIRUS INFECTIONS; FEMALE; FOLLOW-UP STUDIES; HUMAN; IMMUNOGLOBULIN G; INFANT; INFANT FOOD; INSULIN ANTIBODIES; LYMPHOCYTE ACTIVATION; MILK; SUPPORT, NON-U.S. GOV'T; T-LYMPHOCYTES; ANIMALS; HUMANS;

EID: 0035988188     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-002-0787-8     Document Type: Article

References (10)

1. Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice
2. Autoantibody appereance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes. The 2-year analysis of the German BABYDIAB study
3. Cow's milk formula feeding induces primary immunization to insulin in infants at genetic risk for type 1 diabetes
4. The effect of cow milk exposure and maternal type 1 diabetes on cellular and humoral immunization to dietary insulin in infants at genetic risk for type 1 diabetes
5. Enterovirus infection as a risk factor beta-cell autoimmunity in a prospectively observed birth-cohort - The Finnish Diabetes Prediction and Prevention (DIPP) study
6. Enterovirus infections and enterovirus specific T-cell responses in infancy
7. Increased beta-lactoglobulin absorption during rotavirus enteritis in infants: Relationship to sugar permeability
8. Expression of a dietary protein in E. coli renders it strongly antigenic to gut lymphoid tissue
9. Induction of bystander T cell proliferation by viruses and type I interferon in vivo
10. Association between rotavirus infection and pancreatic islet autoimmunity in children at risk of developing type 1 diabetes