Efficient folding of the FcεRI α-chain membrane-proximal domain D2 depends on the presence of the N-terminal domain D1

Journal of Molecular Biology

Volumn 322, Issue 4, 2002, Pages 815-825

  Vangelista, Luca ^a   Cesco Gaspere, Michela ^a   Lamba, Doriano ^a,b   Burrone, Oscar ^a  

^a INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

^b CNR   (Italy)

Author keywords

Domain swapping; Fc RI; Folding in vivo; Intramolecular chaperone; Molecular modelling

Indexed keywords

CHAPERONE; DISULFIDE; IMMUNOGLOBULIN E; MEMBRANE PROTEIN; POLYPEPTIDE; PROTEIN; PROTEIN FCEPSILONRI; UNCLASSIFIED DRUG; HYBRID PROTEIN; IMMUNOGLOBULIN E RECEPTOR;

ALPHA CHAIN; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DIMERIZATION; ENDOPLASMIC RETICULUM; GOLGI COMPLEX; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN GLYCOSYLATION; PROTEIN ISOLATION; PROTEIN LOCALIZATION; PROTEIN SECRETION; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; CHO CELL; GENETICS; HAMSTER; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE;

MAMMALIA;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL MEMBRANE; CHO CELLS; CRICETINAE; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, IGE; RECOMBINANT FUSION PROTEINS;

EID: 0035988174     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00853-7     Document Type: Article

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