Delayed Type Hypersensitivity response to recall antigens does not accurately reflect immune competence in advanced stage breast cancer patients

Breast Cancer Research and Treatment

Volumn 74, Issue 1, 2002, Pages 17-23

  Schiffman, Kathy ^a   Rinn, Kristine ^a   Disis, Mary L ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Anergy; Cancer vaccines; DTH; Immunity; T cell

Indexed keywords

CANCER VACCINE; ONCOPROTEIN; TETANUS TOXOID; TUMOR ANTIGEN; ANTIGEN;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER STAGING; CELLULAR IMMUNITY; CLINICAL TRIAL; CLONAL ANERGY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; FEMALE; HUMAN; HUMAN CELL; IMMUNOCOMPETENCE; LUNG CANCER; MAJOR CLINICAL STUDY; MONONUCLEAR CELL; ONCOGENE NEU; OVARY CANCER; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; T LYMPHOCYTE; BREAST TUMOR; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; MIDDLE AGED; PATHOLOGY; PROTO ONCOGENE; VACCINATION;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS; BREAST NEOPLASMS; CANCER VACCINES; FEMALE; GENES, ERBB-2; HUMAN; HYPERSENSITIVITY, DELAYED; IMMUNE TOLERANCE; MIDDLE AGE; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; T-LYMPHOCYTES; TETANUS TOXOID; VACCINATION; HUMANS; MIDDLE AGED;

EID: 0035987934     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016009317796     Document Type: Article

References (21)

1. Immunosuppressive factors: Role in cancer development and progression
2. Distinctions between CD8+ and CD4+ T-cell regenerative pathways result in prolonged T-cell subset imbalance after intensive chemotherapy
3. Constraints on CD4 recovery postchemotherapy in adults: Thymic insufficiency and apoptotic decline of expanded peripheral CD 4 cells
4. Generation of immunity to the HER-2/neu oncogenic protein in patients with breast and ovarian cancer using a peptide-based vaccine
5. Immunization with a HER-2/neu helper peptide vaccine generates HER-2/neu CD8 T-cell immunity in cancer patients
6. Immune cell populations in cutaneous delayed-type hypersensitivity
7. Assessment of delayed-type hypersensitivity in man: A comparison of the 'Multitest' and conventional intradermal injection of six antigens
8. Killing of target cells by lymphocytes: A mechanistic view
9. Adoptive T cell therapy of tumors: Mechanisms operative in the recognition and elimination of tumor cells
10. Pathways of T-cell regeneration in mice and humans: Implications for bone marrow transplantation and immunotherapy
11. Cancer vaccines: Reborn or just recycled?
12. Delayed type hypersensitivity response (DTH) is an accurate predictor of peripheral blood T cell immunity after HER-2/neu peptide immunization
13. Delayed cutaneous hypersensitivity in normals: Choice of antigens and comparison to in vitro assays of cell-mediated immunity
14. Relationship between cutaneous delayed hypersensitivity and cell-mediated immunity in vitro responses assessed by diphtheria and tetanus toxoids
15. Enhanced delayed hypersensitivity skin test reactivity with serial testing in healthy volunteers
16. Serial delayed cutaneous hypersensitivity skin testing with multiple recall antigens in healthy volunteers: Booster effect study
17. Anergic response to delayed hypersensitivity skin testing. A predictor of early mortality in heart transplant recipients
18. Tuberculin and anergy testing in HIV-seropositive and HIV-seronegative persons
19. In vivo and in vitro cell-mediated immunity to tetanus toxoid in adults
20. A population-based serologic survey of immunity to tetanus in the United States
21. Circulating Candida antigens and antibodies: Useful markers of candidemia