Isolation and characterization of 14 additional genes specifying the anaerobic biosynthesis of cobalamin (vitamin B12) in Propionibacterium freudenreichii (P. shermanii)

Microbiology

Volumn 148, Issue 6, 2002, Pages 1845-1853

  Roessner, Charles A ^a   Huang, Ke Xue ^a   Warren, Martin J ^a   Raux, Evelyne ^a   Scott, A Ian ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Genetic linkage; Hem operon; Metabolic regulation; Methylmalonyl CoA mutase; Transcarboxylase

Indexed keywords

BACTERIAL ENZYME; CARBOXYLTRANSFERASE; COBALAMIN; COBALT DERIVATIVE; COBAMAMIDE; METHYLMALONYL COENZYME A MUTASE; OXIDOREDUCTASE; OXYGEN; PROPIONIC ACID; UROPORPHYRINOGEN; COBALT; COBYRINIC ACID; CYANOCOBALAMIN; DRUG DERIVATIVE; METHYLTRANSFERASE; UROPORPHYRIN III C METHYLTRANSFERASE; UROPORPHYRIN-III C-METHYLTRANSFERASE;

ANAEROBIC CAPACITY; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; GENE CLUSTER; GENE FUNCTION; GENE ISOLATION; GENETIC ANALYSIS; GENETIC CODE; GENETIC LINKAGE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPERON; PRIORITY JOURNAL; PROPIONIBACTERIUM FREUDENREICHII SHERMANII; REGULATORY MECHANISM; ANAEROBIC GROWTH; BACTERIAL GENE; CONSENSUS SEQUENCE; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; PROPIONIBACTERIUM; TRANSPORT AT THE CELLULAR LEVEL;

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); PROKARYOTA; PROPIONIBACTERIUM; PROPIONIBACTERIUM FREUDENREICHII; PROPIONIBACTERIUM FREUDENREICHII SUBSP. SHERMANII; PROPIONIBACTERIUM SHERMANII; UNCULTURED ACTINOMYCETE;

ANAEROBIOSIS; BASE SEQUENCE; BIOLOGICAL TRANSPORT; CLONING, MOLECULAR; COBALT; CONSENSUS SEQUENCE; GENES, BACTERIAL; METHYLTRANSFERASES; MOLECULAR SEQUENCE DATA; OPERON; PROPIONIBACTERIUM; UROPORPHYRINOGENS; VITAMIN B 12;

EID: 0035987288     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/00221287-148-6-1845     Document Type: Article

References (38)

1. Cloning of the luciferase structural genes from Vibrio harveyi and expression of bioluminescence in Escherichia coli
2. 12
3. 12: How the problem of its biosynthesis was solved
4. 12 synthesis and propanediol degradation
5. Genetic and sequence analysis of an 8.7-kilobase Pseudomonas denitrificans fragment involved in transformation of precorrin-2 to cobyrinic acid
6. 12 synthesis in Salmonella typhimurium, insertion of cobalt
7. + gene of Escherichia coli K-12
8. The Propionibacterium freudenreichii hemYHBXRL gene cluster which encodes enzymes and a regulator involved in the biosynthetic pathway from glutamate to protoheme
9. 12) de novo under anaerobic growth conditions
10. Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions
11. Cloning, sequencing and expression of pyrophosphate-dependent phosphofructokinase from Propionibacterium freudenreichii
12. Altered cobalamin metabolism in Escherichia coli btuR mutants affects btuB gene regulation
13. Cloning and structural characterization of the genes coding for adenosylcobalamin-dependent methylmalonyl-CoA mutase from Propionibacterium shermanii
14. Adenosylcobalamin inhibits ribosome binding to btuB RNA
15. Effect of the oxygen supply on pattern of growth and corrinoid and organic acid production of Propionibacterium shermanii
16. 12) biosynthetic genes: Functional studies in S. typhimurium and Escherichia coli
17. 12) and siroheme biosynthesis
18. 12) biosynthesis: Identification and characterization of a Bacillus megaterium cobI operon
19. Expression of 9 Salmonella typhimurium enzymes for cobinamide biosynthesis: Identification of the 11-methyl and 20-methyl transferases of corrin biosynthesis
20. 12 biosynthetic enzymes
21. 12: Variations on a central theme
22. The poc locus is required for 1,2-propanediol-dependent transcription of the cobalamin biosynthetic (cob) and propanediol utilization (pdu) genes of Salmonella typhimurium
23. 12) biosynthetic genes of Salmonella typhimurium
24. DNA sequencing with chain-terminating inhibitors
25. 12
26. Cloning, sequencing and expression of the uroporphyrinogen III methyltransferase cobA gene of Propionibacterium freudenreichii (shermanii)
27. Intermediary metabolism of cobyrinic acid
28. 12: Factor IV, a new intermediate in the anaerobic pathway
29. The Escherichia coli cysG gene encodes the multifunctional enzyme, siroheme synthase
30. Cloning, sequencing and overexpression of cobA which encodes ATP: Corrinoid adenosyltransferase in Salmonella typhimurium
31. Primary structure of the 5S subunit of transcarboxylase as deduced from the genomic DNA structure
32. Primary structure of the monomer of the 12S subunit of transcarboxylase as deduced from DNA and characterization of the product expressed in Escherichia coli
33. Genetic characterization of the pdu operon: Use of 1,2-propanediol in Salmonella typhimurium
34. Biosynthesis of vitamin B12: Concerning the identity of the two-carbon fragment eliminated during anaerobic formation of cobyrinic acid
35. Gene dissection reveals that the E. coli cysG gene encodes a multifunctional enzyme
36. Improved M13 phage cloning vectors and host strains: Nucleotide sequences of the M13mp18 and pUC19 vectors