Expression of cathepsin B, D and L protein in juvenile idiopathic arthritis

Autoimmunity

Volumn 35, Issue 3, 2002, Pages 221-224

  Taubert, H ^a   Riemann, D ^a   Kehlen, A ^a   Meye, A ^a   Bartel, F ^a   John, V ^a   Brandt, J ^a   Bache, M ^a   Wurl P ^b   Schmidt, H ^a   Weber, E ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Cathepsin B; Cathepsin D; Cathepsin H; Fibroblast like synoviocytes; Juvenile idiopathic arthritis; Rheumatoid arthritis

Indexed keywords

AUROTHIOMALATE; AZATHIOPRINE; CATHEPSIN B; CATHEPSIN D; CATHEPSIN H; CATHEPSIN L; CHLORAMBUCIL; CHLOROQUINE; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; GOLD; METHOTREXATE; NONSTEROID ANTIINFLAMMATORY AGENT; PREDNISONE; PROTEINASE; SALAZOSULFAPYRIDINE; CATHEPSIN; CYSTEINE PROTEINASE;

ADOLESCENT; ADULT; ARTICLE; AUTOIMMUNE DISEASE; CARTILAGE MATRIX; CHILD; CHILDHOOD DISEASE; CONTROLLED STUDY; DISEASE COURSE; HUMAN; HUMAN CELL; HUMAN TISSUE; JOINT DESTRUCTION; JUVENILE RHEUMATOID ARTHRITIS; PANNUS; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SYNOVECTOMY; SYNOVIOCYTE; SYNOVIUM; WESTERN BLOTTING; AGED; ENZYMOLOGY; MIDDLE AGED; PHYSIOLOGY; PRESCHOOL CHILD;

ADOLESCENT; ADULT; AGED; ARTHRITIS, JUVENILE RHEUMATOID; BLOTTING, WESTERN; CATHEPSIN B; CATHEPSIN D; CATHEPSINS; CHILD; CHILD, PRESCHOOL; HUMAN; MIDDLE AGE; SUPPORT, NON-U.S. GOV'T; CYSTEINE ENDOPEPTIDASES; HUMANS; MIDDLE AGED;

EID: 0035986702     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.1080/08916930290031676     Document Type: Article

References (20)

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3. Cysteine proteinases in arthritis and inflammation
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6. Differential expression of cathepsins B and L compared with matrix metalloproteinases and their respective inhibitors in rheumatoid and osteoarthritis
7. Selective induction of the secretion of cathepsins B and L by cytokines in synovial fibroblast-like cells
8. Alternative splicing of the 5′ region of cathepsin B pre-messenger RNA in rheumatoid synovial tissue
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10. The p53 status in juvenile chronic arthritis and rheumatoid arthritis
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12. Monoclonal antibodies against cathepsin L and procathepsin L of different species
13. Cartilage proteoglycan aggregate is degraded more extensively by cathepsin L than by cathepsin B
14. Cathepsins B and L in synovial fluids from patients with rheumatoid arthritis and the effect of cathepsin B on the activation of prourokinase
15. Evidence that aspartic proteinase is involved in the proteolytic processing event of cathepsin L in lysosomes
16. The effects of fluoromethyl ketone inhibitors of cathepsin B on adjuvant induced arthritis
17. Cysteine proteinase inhibitors decrease articular cartilage and bone destruction in chronic inflammatory arthritis
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19. Effects of lysosomal cathepsin B, plasmin and kallikrein, and spontaneous activation
20. Physiological mechanisms for metalloproteinase activation