Alternative splicing during chondrogenesis: Modulation of fibronectin exon EIIIA splicing by SR proteins

Journal of Cellular Biochemistry

Volumn 86, Issue 1, 2002, Pages 45-55

  Kuo, Bruce A ^a   Uporova, Tatiana M ^a   Liang, Hongyan ^b   Bennett, Vickie D ^a   Tuan, Rocky S ^a   Norton, Pamela A ^a,b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Alternative splicing; Chondrogenesis; Fibronectin; SR proteins

Indexed keywords

FIBRONECTIN; MEMBRANE PROTEIN; MESSENGER RNA; NUCLEAR PROTEIN; PHOSPHOPROTEIN; RNA BINDING PROTEIN; SERINE ARGININE RICH SPLICING PROTEINS; SERINE-ARGININE-RICH SPLICING PROTEINS;

ALTERNATIVE RNA SPLICING; ARTICLE; CARTILAGE CELL; CHICKEN; CHONDROGENESIS; CONTROLLED STUDY; EXON; HELA CELL; HUMAN; HUMAN CELL; IMMUNOBLOTTING; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; RNA ANALYSIS; SARCOPLASMIC RETICULUM; ANIMAL; CELL CULTURE; CHEMISTRY; CYTOLOGY; GENETIC TRANSFECTION; GENETICS; MESODERM; METABOLISM; PROTEIN BINDING; REGULATORY RNA SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ALTERNATIVE SPLICING; ANIMALS; CELLS, CULTURED; CHICKENS; CHONDROCYTES; CHONDROGENESIS; EXONS; FIBRONECTINS; HELA CELLS; HUMANS; MESODERM; NUCLEAR PROTEINS; PHOSPHOPROTEINS; PROTEIN BINDING; REGULATORY SEQUENCES, RIBONUCLEIC ACID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA-BINDING PROTEINS; TRANSFECTION;

EID: 0035986584     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.10188     Document Type: Article

References (56)

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3. Finding splice sites within a wilderness of RNA
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5. A novel bipartite splicing enhancer modulates the differential processing of the human fibronectin EDA exon
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13. The superfamily of arginine/serine-rich splicing factors
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18. The splicing factor SRp20 modifies splicing of its own mRNA and ASF/SF2 antagonizes this regulation
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21. A splicing enhancer in the human fibronectin alternate exon ED1 interacts with SR proteins and stimulates U2 snRNP binding
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34. In vitro splicing of fibronectin pre-RNAs
35. Isolation and characterization of proteoglycans from the Swarm rat chondrosarcoma
36. Alternative exon splicing within the amino-terminal nontriple-helical domain of the rat pro-α1(XI) collagen chain generates multiple forms of the mRNA transcript which exhibit tissue-dependent variation
37. Fibronectin isoform distribution in the mouse. I. The alternatively spliced EIIIB,EIIIA and V segments show widespread codistribution in the developing mouse embryo
38. The protein kinase Clk/Sty directly modulates SR protein activity: Both hyper- and hypophosphorylation inhibit splicing
39. A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer
40. A conserved family of nuclear phosphoproteins localized to sites of polymerase II transcription
41. Differential expression of a cysteine-rich domain in the amino-terminal propeptide of type II (cartilage) procollagen by alternative mRNA splicing
42. Developmental regulation of SR protein phosphorylation and activity
43. The mammalian homolog of suppressor-of-white-apricot regulates alternative mRNA splicing of CD45 exon4 and fibronectin IIICS
44. Identification and characterization of three members of the human SR family of pre-mRNA splicing factors
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50. Alternative splicing during chondrogenesis: cis and trans factors involved in splicing of fibronectin exon EIIIA
51. Overexpression of the SR proteins ASF/SF2 and SC35 influences alternative splicing in vivo in diverse ways
52. A complex of nuclear proteins mediates SR protein binding to a purine-rich splicing enhancer
53. SR proteins: A conserved family of pre-mRNA splicing factors
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55. Alternative splicing of ED-A and ED-B sequences of fibronectin pre-mRNA differs in chondrocytes from different cartilaginous tissues and can be modulated by biological factors
56. Alternative mRNA processing occurs in the variable region of the pro-α1(XI) and pro-α2(XI) collagen chains