Inhaled pinacidil, an ATP-sensitive K+ channel opener, and moguisteine have potent antitussive effect in guinea pigs

Japanese Journal of Pharmacology

Volumn 89, Issue 2, 2002, Pages 171-175

  Morita, Kayo ^a   Onodera, Kenji ^a   Kamei, Junzo ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

Antitussive effect; ATP sensitive K+ channel; Cough reflex; Moguisteine; Peripherally acting non narcotic antitussive drug

Indexed keywords

17 METHYLNALOXONE; ADENOSINE TRIPHOSPHATE; ANTITUSSIVE AGENT; CAPSAICIN; DIHYDROCODEINE; GLIBENCLAMIDE; MOGUISTEINE; NARCOTIC ANTITUSSIVE AGENT; PINACIDIL; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL STIMULATING AGENT; UNCLASSIFIED DRUG; CODEINE; DRUG DERIVATIVE; NALOXONE; THIAZOLE DERIVATIVE; THIAZOLIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; COUGHING; DOSE RESPONSE; DRUG ACTIVITY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENCY; GUINEA PIG; MALE; NONHUMAN; STATISTICAL SIGNIFICANCE; TRACHEOBRONCHIAL TREE; ANIMAL; CHEMICALLY INDUCED DISORDER; INHALATIONAL DRUG ADMINISTRATION; METABOLISM;

ADENOSINE TRIPHOSPHATE; ADMINISTRATION, INHALATION; ANIMALS; ANTITUSSIVE AGENTS; CAPSAICIN; CODEINE; COUGH; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ANTAGONISM; GLYBURIDE; GUINEA PIGS; MALE; NALOXONE; PINACIDIL; POTASSIUM CHANNELS; THIAZOLES; THIAZOLIDINES;

EID: 0035986297     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.89.171     Document Type: Article

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