Effect of low level zinc pretreatment on zinc-mediated toxicity in different lung cell lines

Biological Trace Element Research

Volumn 88, Issue 1, 2002, Pages 45-57

  Walther, U I ^a   Muckter H ^a   Wallner, B ^a   Bergen, U ^a   Duggen, S ^a   Unsinn, G ^a   Walther, S C ^a   Fichtl, B ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Glutathione; Protein synthesis inhibitors; Zinc toxicity; Zn2+

Indexed keywords

AMANITIN; CYCLOPHOSPHAMIDE; DACTINOMYCIN; GLUTATHIONE; METALLOTHIONEIN; PROTEIN SYNTHESIS INHIBITOR; ZINC; GLUTATHIONE REDUCTASE; LACTATE DEHYDROGENASE; NUCLEIC ACID SYNTHESIS INHIBITOR;

ANIMAL CELL; ARTICLE; BLOOD SAMPLING; CELL LINE; CELL PROTECTION; CYTOTOXICITY; ENZYME ACTIVITY; INTOXICATION; LUNG ALVEOLUS CELL; MESSENGER RNA SYNTHESIS; NONHUMAN; OCCUPATIONAL EXPOSURE; PROTEIN CONTENT; PROTEIN SYNTHESIS INHIBITION; BIOSYNTHESIS; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; LUNG; METABOLISM;

CELL LINE; GLUTATHIONE; GLUTATHIONE REDUCTASE; LACTATE DEHYDROGENASE; LUNG; NUCLEIC ACID SYNTHESIS INHIBITORS; PROTEIN SYNTHESIS INHIBITORS; ZINC; L-LACTATE DEHYDROGENASE;

ANIMALIA;

EID: 0035986179     PISSN: 01634984     EISSN: None     Source Type: Journal    
DOI: 10.1385/BTER:88:1:45     Document Type: Article

References (29)

1. Effects of zinc on rat hepatoma HTC cells and primary cultured rat hepatocytes
2. Influence of glutathione on zinc-mediated cellular toxicity
3. Induction of metallothionein synthesis by glutathione depletion after trans- and cis-stilbene oxide administration in rats
4. The function of metallothionein
5. Inhibition of cell membrane lipid peroxidation by cadmium- and zinc-metallothioneins
6. Metal fume fever - A review
7. Die zinknebelver-giftung und ihre behandlung. I. Chemische und toxikologische grundlagen
8. II. Symptomatologie und verlauf der vergiftung
9. Pulmonary damage after modest exposure to zinc chloride smoke
10. Disaggregation of the tissue and primary culture
11. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues
12. Development of a cell culture model system for routine testing of substances inducing oxidative stress
13. Lactate dehydrogenase. UV-method with pyruvate and NADH
14. Minimization of variation in the response to different proteins of the Coomassie Blue G dye-binding assay for protein
15. GSSG reductase activity a further factor influencing zinc-mediated toxicity in lung cell lines
16. Glutathione content and growth in A549 human lung carcinoma cells
17. Effect of hydrocortisone pretreatment on decreased protein synthesis in various lung cells after zinc chloride incubation
18. Multiple endpoint measurements to evaluate the intrinsic cellular toxicity of chemicals
19. Zinc-induced tolerance to cadmium cytotoxicity without metallothionein induction in cultured bovine aortic endothelial cells
20. Coordinate regulation of mouse metallothionein I and II genes by heavy metals and glucocorticoids
21. Metal-regulated transcription in eukaryotes
22. Corticosterone enhances the zinc and interleukin-6-mediated induction of metallothionein in cultured rat hepatocytes
23. Metallothionein induction attenuates the effects of glutathione depletors in rat hepatocytes
24. Production of metallothionein and heat-shock proteins in response to metals
25. Influence of zinc on protein metabolism in various lung cell lines
26. Cloning and functional characterization of mammalian zinc transporter that confers resistance to zinc
27. Mammalian zinc transporters
28. ZnT-2, a mammalian protein that confers resistance to zinc by facilitating vesicular sequestration
29. ZnT-3, a putative transporter of zinc into synaptic vesicles