A new paradigm of chemotherapy for gastric cancer: Speeding up, and more clinical trials to catch up

Gastric Cancer

Volumn 5, Issue 2, 2002, Pages 55-57

  Sakamoto, Junichi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIALLERGIC AGENT; ANTINEOPLASTIC AGENT; CISPLATIN; CORTICOSTEROID; FLUOROPYRIMIDINE; FLUOROURACIL; GRANULOCYTE COLONY STIMULATING FACTOR; HISTAMINE H1 RECEPTOR ANTAGONIST; HISTAMINE H2 RECEPTOR ANTAGONIST; IRINOTECAN; PACLITAXEL; TEGAFUR; TS 1;

ADJUVANT CHEMOTHERAPY; ANTINEOPLASTIC ACTIVITY; CANCER COMBINATION CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; CLINICAL TRIAL; DRUG EFFECT; DRUG EFFICACY; DRUG HYPERSENSITIVITY; DRUG INDICATION; DRUG INDUCED DISEASE; DRUG RESPONSE; EDITORIAL; HUMAN; JAPAN; LEUKOPENIA; NEUTROPENIA; PRACTICE GUIDELINE; PRIORITY JOURNAL; STOMACH CANCER; STOMACH SURGERY; TREATMENT INDICATION; NOTE; PHASE 2 CLINICAL TRIAL; STOMACH TUMOR;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CLINICAL TRIALS, PHASE II; HUMAN; PACLITAXEL; STOMACH NEOPLASMS; HUMANS;

EID: 0035986167     PISSN: 14363291     EISSN: None     Source Type: Journal    
DOI: 10.1007/s101200200009     Document Type: Editorial

References (22)

1. Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction
2. Adjuvant mitomycin and fluorouracil followed by oral uracil plus tegafur in serosa-negative gastric cancer: A randomised trial
3. Randomized trial of adjuvant chemotherapy with MCF followed by oral fluorouracil in serosanegative gastric cancer: JCOG Study 9206-1
4. Randomized trial comparing epirubicin, cisplatin, and fluorouracil versus fluorouracil, doxorubicin, and methotrexate in advanced esophagogastric cancer
5. Final results of randomized phase III trial of sequential high-dose methotrexate, fluorouracil, and doxorubicin versus etoposide, leucovorin, and fluorouracil versus infusional fluorouracil and cisplatin in advanced gastric cancer: A trial of the European Organization for Research and Treatment of Cancer
6. Adjuvant chemotherapy of gastric cancer has to be fundamentally reconsidered (in Japanese)
7. Taxol stabilizes microtubules in mouse fibroblast cells
8. Taxol: A novel investigational antimicrotubule agent
9. Paclitaxel affects microtubule dynamics and apoptosis
10. Mechanisms of taxol-induced cell death are concentration dependent
11. Phase I study of taxol administrated as a short IV infusion daily for 5 days
12. Nonlinear pharmacokinetics and metabolism of paclitaxel and its pharmacokinetic/pharmacodynamic relationship in humans
13. Weekly paclitaxel with and without concurrent radiation therapy: Toxicity, pharmacokinetics, and response
14. An early phase II study of a 3-h infusion of paclitaxel for advanced gastric cancer
15. Phase II trial of paclitaxel by 3-h infusion for advanced gastric cancer with short premedication for prophylaxis against paclitaxel-associated hypersensitivity reactions
16. Phase II study of paclitaxel with 3-h infusion in patients with advanced gastric cancer
17. Paclitaxel resistance in non-small-cell lung cancer associated with beta-tubulin gene mutations
18. Development of two radioimmunoassays to detect paclitaxel in sera and in cerebrospinal, ascitic, and pleural fluids
19. FOLFIRI followed by FOLFOX followed by FOLFIRI in metastatic colorectal cancer: Which is the best sequence? safety and preliminary efficacy results of a randomized phase III study