Peptoid residues and β-turn formation

Journal of Peptide Science

Volumn 8, Issue 6, 2002, Pages 241-252

  Rainaldi, Mario ^a   Moretto, Vittorio ^a   Crisma, Marco ^a   Peggion, Evaristo ^a   Mammi, Stefano ^a   Toniolo, Claudio ^a,c   Cavicchioni, Giorgio ^b  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

^c CNR   (Italy)

Author keywords

turn; Conformational analysis; Hydrogen bond; Infrared absorption; Nuclear magnetic resonance; Peptoids

Indexed keywords

CHLOROFORM; GLYCINE DERIVATIVE; HYDROGEN; SARCOSINE; DRUG DERIVATIVE; GLYCINE; ISOPROTEIN; N ISOBUTYLGLYCINE; N-ISOBUTYLGLYCINE; PEPTOID;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; HYDROGEN BOND; INFRARED SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; RADIATION ABSORPTION; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE; PROTEIN SECONDARY STRUCTURE; SYNTHESIS;

AMINO ACID SEQUENCE; CHLOROFORM; GLYCINE; HYDROGEN BONDING; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTOIDS; PROTEIN ISOFORMS; PROTEIN STRUCTURE, SECONDARY; SARCOSINE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 0035985627     PISSN: 10752617     EISSN: None     Source Type: Journal    
DOI: 10.1002/psc.392     Document Type: Article

References (66)

1. Peptide backbone modifications: A structure-activity analysis of peptides containing amide bond surrogates. Conformational constraints, and related backbone modifications
2. Emerging approaches in the molecular design of receptor-selective peptide ligands: Conformational, topographical and dynamic considerations
3. Peptide conformation mimetics
4. Evaluation of the stability of peptides and pseudopeptides as a tool in peptide drug design
5. Constrained peptides: Models of bioactive peptides and protein substructures
6. Peptidomimetics for receptor ligands. Discovery, development, and medical perspectives
7. Conformationally restricted amino acids and dipeptides, (non)peptidomimetics and secondary structure mimetics
8. Case histories of peptidomimetics: Progression from peptides to drugs
9. Peptidomimetics: Tailored enzyme inhibitors
10. Constrained peptides as binding entities
11. Design of peptides, proteins, and peptidomimetics in χ space
12. Design and synthesis of conformationally constrained amino acids as versatile scaffolds and peptide mimetics
13. Conformationally restricted peptides through short-range cyclization
14. Peptoids: A modular approach to drug discovery
15. 'Shifty peptides': A novel topochemical modification; model peptides and substance P related analogs
16. Efficient method for the preparation of peptoids [oligo (N-substituted glycines)] by submonomer solid-phase synthesis
17. 13C resonances of N-substituted glycine peptoids
18. NMR determination of the major solution conformation of a peptoid pentamer with chiral side chains
19. Peptoid oligomers with α-chiral, aromatic side chains: Effects of chain length on secondary structure
20. Peptoid oligomers with α-chiral, aromatic side chains: Sequence requirements for the formation of stable peptoid helices
21. Extreme stabilities of helices formed by water-soluble poly-N-substituted glycines (polypeptoids) with α-chiral side chains
22. Collagen-based structures containing the peptoid residue N-isobutylglycine (Nleu): Synthesis and biophysical studies of Gly-Pro-Nleu sequences by circular dichroism, ultraviolet absorbance and optical rotation
23. 1H NMR, CD, and molecular modeling
24. Collagen-like triple helices incorporating peptoid residues
25. 2+ complex of a linear N-protected glycyl-dipeptoid derivative
26. 1H NMR and molecular modeling
27. Collagen mimetics
28. Incorporation of achiral peptoid-based trimeric sequences into collagen mimetics
29. Triple helical stabilities of guest-host collagen mimetic structures
30. Peptides and peptoids. A quantum chemical structure comparison
31. Secondary structure formation in N-substituted peptides
32. Pro-D-NMe-amino acid and D-Pro-NMe-amino acid: Simple, efficient reverse-turn constraints
33. Conformational analysis of reverse-turn constraints by N-methylation and N-hydroxylation of amide bonds in peptides and non-peptide mimetics
34. β-Turn formation of short peptides in various mixed solvents: Analysis of the chemical shift differences between two α-protons of N-methylglycyl residues
35. Experimental investigations on the backbone folding of proline-containing model tripeptides
36. Modulations conformationnelles du repliement β en série peptidique et pseudopeptidique
37. Proton magnetic resonance study of linear sarcosine oligomers
38. Conformational analysis of the 20 naturally occurring amino acid residues using ECEPP
39. Stereochemical criteria for polypeptides and proteins. V. Conformation of a system of three-linked peptide units
40. Intramolecularly hydrogen-bonded peptide conformations
41. Turns in peptides and proteins
42. Isolation and structure of hypothalamic MSH release-inhibiting hormone
43. Regulation of formation and proposed structure of the factor inhibiting the release of melanocyte-stimulating hormone
44. Improved spectral resolution in COSY proton NMR spectra of proteins via double quantum filtering
45. Rapid-pulsing artifacts in double-quantum-filtered COSY
46. MLEV-17-based two-dimensional homonuclear magnetization transfer spectroscopy
47. 1H spin system identification in macro-molecules
48. Structure determination of a tetrasaccharide: Transient nuclear Overhauser effect in the rotating frame
49. Practical aspects of two-dimensional transverse NOE spectroscopy
50. Cross relaxation without TOCSY: Transverse rotating frame Overhauser effect spectroscopy
51. Reliable two-dimensional rotating-frame cross-relaxation measurements in coupled spin systems
52. Correlation of proton and nitrogen-15 chemical shifts by multiple quantum NMR
53. 13C assignments from sensitivity-enhanced detection of heteronuclear multiple-bond connectivity by 2D multiple quantum NMR
54. Improved resolution in proton-detected heteronuclear long-range correlation
55. Increased HMBC sensitivity for correlating poorly resolved proton multiplets to carbon-13 using selective or semi-selective pulses
56. Eine neue Methode zur Synthese von Peptiden: Activierung der Carboxylgruppe mit Dicyclohexylcarbodiimid unter Zusatz von 1-Hydroxybenzotriazolen
57. 1-Hydroxy-7-azabenzotriazole. An efficient peptide coupling reagent
58. Control of enantioselectivity in the formation of a model alaninamide from a 2-bromopropanamide
59. Étude expérimentale de la conformation de molécules dipeptidiques. Comparaison avec les prévisions théorique
60. Conformational analysis of linear peptides: 5. Spectroscopic characterization of β-turns in Aib-containing oligopeptides in chloroform
61. 10- and α-helices and β-bend ribbon structures in organic solution and in model biomembranes by Fourier transform infrared spectroscopy
62. The γ-turn, a possible folded conformation of the polypeptide chain. Comparison with the β-turn
63. Preferred conformation of the tert-butoxycarbonyl-amino group
64. Sensitivity-enhanced two-dimensional heteronuclear relayed coherence transfer NMR spectroscopy
65. The stereochemistry of peptides containing α-aminoisobutyric acid