Bioavailability and in vitro oesophageal sticking tendency of hydroxypropyl methylcellulose capsule formulations and corresponding gelatine capsule formulations

European Journal of Pharmaceutical Sciences

Volumn 15, Issue 5, 2002, Pages 479-488

  Honkanen, Outi ^a,b   Pia, Laaksonen ^a   Janne, Marvola ^a   Sari, Eerikäinen ^a   Raimo, Tuominen ^a   Martti, Marvola ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b University Pharmacy ^*  (Finland)

Author keywords

Adherence to the oesophagus; Bioavailability; Gelatine capsule; Hydroxypropyl methylcellulose capsule; Ibuprofen; Sustained release

Indexed keywords

BIOAVAILABILITY;

ABSORPTION; GELATION; MOLECULAR WEIGHT; VISCOSITY;

CELLULOSE;

HYDROXYPROPYLMETHYLCELLULOSE; IBUPROFEN; POLYMER; DRUG DERIVATIVE; GELATIN; METHYLCELLULOSE;

ADULT; ANIMAL TISSUE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG BIOAVAILABILITY; DRUG RELEASE; ESOPHAGUS; FEMALE; GELATINIZATION; HUMAN; HUMAN EXPERIMENT; IN VITRO STUDY; MALE; MICROCAPSULE; MOLECULAR WEIGHT; NONHUMAN; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; POWDER; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SUSTAINED RELEASE PREPARATION; VOLUNTEER; AREA UNDER THE CURVE; BIOAVAILABILITY; BLOOD; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECT; METABOLISM; RECTAL DRUG ADMINISTRATION;

ADMINISTRATION, ORAL; ADMINISTRATION, RECTAL; ADULT; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CAPSULES; CHEMISTRY, PHARMACEUTICAL; COMPARATIVE STUDY; CROSS-OVER STUDIES; ESOPHAGUS; FEMALE; GELATIN; HUMAN; IBUPROFEN; MALE; METHYLCELLULOSE; SUPPORT, NON-U.S. GOV'T; HUMANS;

EID: 0035984929     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(02)00032-5     Document Type: Article

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