Combination of HCGβ, CA 19-9 and CEA with logistic regression improves accuracy in gastrointestinal malignancies

Anticancer Research

Volumn 22, Issue 3, 2002, Pages 1759-1764

  Louhimo, Johanna ^a   Finne, Patrik ^a   Alfthan, Henrik ^a   Stenman, Ulf Håkan ^a   Haglund, Caj ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

CA 19 9; Cancer; CEA; Diagnosis; Gastrointestinal; HCG ; Logistic regression; Tumour marker

Indexed keywords

CA 19-9 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; CHORIONIC GONADOTROPIN BETA SUBUNIT; TUMOR MARKER;

ADULT; AGED; ALGORITHM; ARTICLE; BILE DUCT CANCER; BLOOD LEVEL; DIAGNOSTIC ACCURACY; DIAGNOSTIC PROCEDURE; DIAGNOSTIC VALUE; DIGESTIVE SYSTEM CANCER; FEMALE; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; PANCREAS CANCER; PRIORITY JOURNAL; BLOOD; COMPARATIVE STUDY; EVALUATION; GASTROINTESTINAL TUMOR; MIDDLE AGED; STATISTICAL MODEL;

ADULT; AGED; AGED, 80 AND OVER; ALGORITHMS; CA-19-9 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN; FEMALE; GASTROINTESTINAL NEOPLASMS; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; TUMOR MARKERS, BIOLOGICAL;

EID: 0035984235     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Human placental and pituitary glycoprotein hormones and their subunits as tumor markers: A quantitative assessment
2. Free human chorionic gonadotropin β subunit in gonadal and nongonadal neoplasms
3. Elevation of free b subunit of human choriogonadotropin and core β fragment of human choriogonadotropin in the serum and urine of patients with malignant pancreatic and biliary disease
4. Beta human chorionic gonadotropin concentrations in serum of patients with pancreatic adenocarcinoma
5. Evidence for the presence of human chorionic gonadotropin (hCG) and free β-subunit of hCG in the human pituitary
6. Malignant transformation of nontrophoblastic cells is associated with the expression of chorionic gonadotropin β genes normally transcribed in trophoblastic cells
7. Specific staining of human chorionic gonadotropin β in benign and malignant gastrointestinal tissues with monoclonal antibodies
8. Human chorionic gonadotropin-beta subunit gene expression in cultured human fetal and cancer cells of different types and origins
9. Have we found the "definitive cancer biomarker"? The diagnostic and therapeutic implications of human chorionic gonadotropin-beta expression as a key to malignancy
10. The effects of beta-human chorionic gonadotrophin on the in vitro growth of bladder cancer cell lines
11. The increase in bladder carcinoma cell population induced by the free beta subunit of human chorionic gonadotrophin is a result of an anti-apoptosis effect and not cell proliferation
12. The prognostic value of CEA, βHCG, AFP, CA125, CA19-9 and C-erb B-2, βHCG immunohistochemistry in advanced colorectal cancer
13. The prognostic value of serum and immunohistochemical tumour markers in advanced gastric cancer
14. Independent prognostic value of preoperative serum markers CA 242, specific tissue polypeptide antigen and human chorionic gonadotrophin beta, but not of carcinoembryonic antigen or tissue polypeptide antigen in colorectal cancer
15. Cancer of the colon: The influence of the no-touch isolation technic on survival rates
16. Choriogonadotropin and its β subunit separated by hydrophobic-interaction chromatography and quantified in serum during pregnancy by time-resolved immunofluorometric assays
17. Concentrations of human choriogonadotropin, its β-subunit, and the core fragment of the β-subunit in serum and urine of men and nonpregnant women
18. A method of comparing the areas under receiver operating characteristic curves derived from the same cases
19. The incidence and significance of serum hCG and CEA in patients with gastrointestinal malignant tumors
20. Multiple markers of malignancy in sera of patients with colorectal carcinoma: Preliminary clinical studies
21. Gonadotropins and their subunits: Basic and clinical studies
22. Immunoreactive human chorionic gonadotropin and its free β subunit in serum and ascites of patients with malignant tumors
23. Predicting the outcome of prostate biopsy in screen-positive men by a multilayer perceptron network