Generalization of ionic partition diagrams to lipophilic compounds and to biphasic systems with variable phase volume ratios

Journal of the American Chemical Society

Volumn 123, Issue 43, 2001, Pages 10684-10690

  Gobry, V ^a   Ulmeanu, S ^a   Reymond, F ^a   Bouchard, G ^b   Carrupt, P A ^b   Testa, B ^b   Girault, H H ^a  

^a EPFL   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

IONIC PARTITION DIAGRAM;

ELECTROCHEMISTRY; EXTRACTION; HYDROPHILICITY; LIPIDS;

CHEMICAL ANALYSIS;

CHEMICAL COMPOUND; LIPOPHILIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; CALCULATION; CHEMICAL ANALYSIS; ELECTROCHEMICAL ANALYSIS; EXTRACTION; HYDROPHILICITY; LIPOPHILICITY; METHODOLOGY; THEORY; VOLUMETRY;

2,4-DINITROPHENOL; ACIDS; ANILINE COMPOUNDS; ELECTROCHEMISTRY; HYDROGEN-ION CONCENTRATION; IONS; KINETICS; LIPIDS; SOLUBILITY; THERMODYNAMICS; WATER;

EID: 0035980392     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja015914f     Document Type: Article

References (20)

1. Voltammetric study of drugs at liquid-liquid interfaces
2. Transfer mechanisms and lipophilicity of ionizable drugs