Conserved Tyrosine-369 in the active site of Escherichia coli copper amine oxidase is not essential

Biochemistry

Volumn 40, Issue 43, 2001, Pages 12808-12818

  Murray, J M ^a,b   Kurtis, C R ^a   Tambyrajah, W ^a,c   Saysell, C G ^a   Wilmot, C M ^a,d   Parsons, M R ^a   Phillips, S E V ^a   Knowles, P F ^a   McPherson, M J ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b YALE UNIVERSITY   (United States)

^c UNIVERSITY OF LEICESTER   (United Kingdom)

^d UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TURNOVER MECHANISM;

ALDEHYDES; AMINES; AMMONIA; CATALYSIS; ESCHERICHIA COLI; HYDROGEN PEROXIDE; MUTAGENESIS; SUBSTRATES;

ENZYME KINETICS;

2 HYDRAZINOPYRIDINE; 6 HYDROXYDOPA; ALDEHYDE; AMINE; AMMONIA; BACTERIAL ENZYME; COPPER AMINE OXIDASE; HYDROGEN; HYDROGEN PEROXIDE; HYDROXYL GROUP; MONOMER; OXIDOREDUCTASE; OXYGEN; PHENETHYLAMINE; PROTON; PYRIDINE DERIVATIVE; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOGENESIS; CATALYSIS; CONFORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DEAMINATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME STRUCTURE; ESCHERICHIA COLI; HYDROGEN BOND; NONHUMAN; OXIDATION; PH; PRIORITY JOURNAL; REDUCTION; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

AMINE OXIDASE (COPPER-CONTAINING); BINDING SITES; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; ELECTRONS; ENZYME INHIBITORS; ESCHERICHIA COLI; HYDROGEN; HYDROGEN-ION CONCENTRATION; KINETICS; MASS SPECTROMETRY; MODELS, CHEMICAL; MODELS, MOLECULAR; MUTAGENESIS; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHENYLALANINE; PROTEIN BINDING; PROTEIN CONFORMATION; PYRIDONES; SPECTROPHOTOMETRY; TIME FACTORS; TYROSINE; ULTRAVIOLET RAYS;

ANIMALIA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0035980283     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi011187p     Document Type: Article

References (66)