Tissue distribution and kinetics of endogenous porphyrins synthesized after topical application of ALA in different vehicles

British Journal of Cancer

Volumn 81, Issue 1, 1999, Pages 13-18

  Casas, A ^a   Fukuda, H ^a   Del C Batlle, A M ^a,b  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b NONE   (Argentina)

Author keywords

5 Aminolaevulinic acid; ALA cream; ALA lotion; ALA PDT; Topical application

Indexed keywords

AMINOLEVULINIC ACID; DRUG VEHICLE; PHOTOSENSITIZING AGENT; PORPHYRIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER THERAPY; CONTROLLED STUDY; CREAM; FECES LEVEL; KIDNEY; KINETICS; LIVER; LOTION; MALE; MOUSE; NONHUMAN; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; SKIN; SPLEEN; TISSUE DISTRIBUTION; TOPICAL DRUG ADMINISTRATION; URINE LEVEL;

ADENOCARCINOMA; ADMINISTRATION, TOPICAL; AMINOLEVULINIC ACID; ANIMALS; KINETICS; MALE; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED BALB C; NEOPLASM TRANSPLANTATION; PHOTOSENSITIZING AGENTS; PORPHYRINS; TISSUE DISTRIBUTION; VEHICLES;

EID: 0032865014     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6690644     Document Type: Article

References (32)

1. Batlle A and Grinstein M (1962) Porphyrin biosynthesis. Studies on the nature of a biosynthetic porphyrin and its identification with the so-called "208" porphyrin. Biochim Biophys Acta 57: 191-194
2. Batlle A, Llambías E, Wider E and Tigier H (1975) Porphyrin biosynthesis in the soybean callus tissue system XV. The effect of growth conditions. Int J Biochem 6: 591-606
3. Dailey H and Smith A (1984) Differential interaction of porphyrins used in photoradiation therapy with ferrochelatase. Biochem J 223: 441-445
4. Doss M and Schmidt A (1971a) Rapid determination of urinary total porphyrins by ion exchange chromatography. Z Klin Chem Klin Biochem 9: 415-418
5. Doss M and Schmidt A (1971b) Quanlitative Bestimmung der 5-Aminolävulinsäure und Porphobilinogen im Urin mit lonenaustauschereromathographic-Fertigsäulen. Z Klin Chem Klin Biochem 9: 99-102
6. Dougherty T, Grindey G, Fiel R, Weishaupt K and Boyle D (1975) Photoradiation therapy II: cure of animal tumours with hematoporphyrin and light. J Natl Cancer Inst 55: 115-121
7. Falk J (1964) Porphyrins and metalloporphyrins In: Biochimica of Biophysica Acta Library Vol. 2. Elsevier: Amsterdam
8. Fritsch C, Verwohlt B, Bolsen K, Ruzicka T and Goerz G (1996) Influence of topical photodynamic therapy with 5-aminolevulinic acid on porphyrin metabolism. Arch Dermatol Res 288: 517-521
9. Fukuda H, Paredes S and Batlle A (1989) Tumour-localizing properties of porphyrins. In vitro studies using the porphyrin precursor, aminolevulinic acid, in free and liposome encapsulated forms. Drug Des Deliv 5: 133-139
10. Fukuda H, Paredes S and Batlle A (1992) Tumour-localizing properties of porphyrins. In vivo studies using free and liposome encapsulated aminolevutinic acid. Comp Biochem Physiol 102B: 433-436
11. Fukuda H, Batlle A and Riley P (1993) Kinetics of porphyrin accumulation in cultured epithelial cells exposed to ALA. Int J Biochem 25: 1407-1410
12. Goof B, Bachor R, Kollias N and Hasan T (1992) Effects of photodynamic therapy with topical application of 5-aminolevulinic acid on normal skin of hairless guinea pigs. J Photochem Photobiol 15: 239-251
13. Grant W, Hopper C, MacRobert A, Speight P and Bown S (1993) Photodynamic therapy of oral cancer: photosensitization with systemic aminolevulinic acid. Lancet 342: 147-148
14. Henderson BW, Vaughan I., Bellnier D, Van Leengoed H, Johnson PG and Oseroff AR (1995) Photosensitization of murine tumour, vasculature and skin by 5-aminolevulinic acid-induced porphyrin. Photochem Photobiol 62: 780-789
15. Kennedy J and Pottier R (1992) Endogenous protoporphyrin IX, a clinically useful photosensitizer for photodynamic therapy. J Photochem Photobiol B 14: 275-292
16. Kennedy J, Pottier R and Pross G (1990) Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience. J Photochem Photobiol B 6: 143-148
17. Kriegmair M, Baumgartner R, Knuechel R, Stepp H, Hofstädter F and Hofstetter A (1996) Detection of early bladder cancer by 5-aminolevulinic acid induced porphyrin fluorescence J Urology 155: 105-110
18. Magee P (1991) Percutaneous absorption: critical factors in transdermal transport. In: Dermatoxicology, Marzulli F and Maibach H (eds) pp. 1-35. Hemisphere: New York
19. Menon J, Becker S, Persad S and Haberman H (1990) Quantitation of hydrogen peroxide formed during UV-visible irradiation of protoporphyrin, coproporphyrin and uroporphyrin. Clin Chim Acta 186: 375-381
20. Navone N, Frisardi Resnik E, Batlle A and Polo C (1988) Porphyrin biosynthesis in human breast cancer. Preliminary mimetic in vitro studies. Med Sci Res 16: 61-62
21. Navune N, Polo C, Frisardi A and Batlle A (1991 ) Mouse mammary carcinoma PBGase and hydroxymethylbilane synthetase. Comp Biochem Physiol B 98: 67-71
22. Peng Q, Moan J, Warloc T, Nesland JM and Rimington C (1992) Distribution and photosensitizing efficiency of porphyrins induced by application of exogenous 5-aminolevulinic acid in mice bearing mammary carcinoma. Int J Cancer 52: 433-443
23. Rougier A and Lotte C (1986) Correlations between horny layer concentration and percutaneous absorption. In: Pharmacology and Skin: I. Skin Pharmacokinetics. Shroot B (ed) Schaeger: Switzerland
24. Schoenfeld N. Epstein O, Lahav M, Mamet R, Shaklai M and Atsmon A (1998) The heme biosynthetic pathway in lymphocytes of patients with malignant lymphoproliferative disorders. Cancer Lett 43: 43-48
25. Schoenfeld N, Mamet R, Nordenberg Y, Shafran M, Babushkin T and Malik Z (1994) Protoporphyrin biosynthesis in melanoma B16 cells stimulated by 5-aminolaevulinic acid and chemical inducers: characterization of photodynamic inactivation. Int J Cancer 56: 106-112
26. Scolnik A, Rubio M, Colombo L, Comolli R and Caro R (1984) Further studies on the bystamine metabolism in the M2 adenocarcinoma. Biomed Pharmacother 38: 465-467
27. Stringer M, Collins P, Robinson D, Stabhles G and Sheehan-dare R (1996) The accumulation of Protoporphyrin IX in plaque psoriasis after topical application of 5-aminolevulinic acid indicates a potential for superficial photodynamic therapy. J Invest Dermatol 107: 76-81
28. Torralba Rodriguez A (1985) Histologia y fisiologia de la piel y sus anejos. Aspectos básicos e implicaciones cosméticas. In: Cosmetología teórico-prática. 13-46. Consejo General de Colegios Oficiales de Farmacéuticos: Madrid
29. UK Coordinating Committee on Cancer Research (1988) UKCCCR Guidelines for the Welfare of Animals in Experimental Neoplasia. UKCCCR: London
30. Van Hillesberg R, Van der Berg J, Kort W, Terpstra O and Wilson J (1992) Selective accumulation of endogenously produced porphyrins in a liver metastasis model in rats. Gastroenterology 103: 647-651
31. With T (1975) Clinical use of porphyrin ester cromatography in urine and feces. Dan Med Bull 22: 74
32. Wolf P, Rieger F, and Kerl H (1993) Topical photodynamic therapy with endogenous porphyrins after application of 5-aminolevulíníc acíd. J Am Acad Dermatol 28: 17-21