A cell system with targeted disruption of the SMN gene: Functional conservation of the SMN protein and dependence of Gemin2 on SMN

Journal of Biological Chemistry

Volumn 276, Issue 13, 2001, Pages 9599-9605

  Wang, Jin ^a   Dreyfuss, Gideon ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; NEUROLOGY; PROTEINS;

GENETIC SYSTEMS;

GENES;

COMPLEMENTARY DNA; GEMIN 2; GENE PRODUCT; SURVIVAL MOTOR NEURON PROTEIN; TETRACYCLINE; UNCLASSIFIED DRUG; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; NERVE PROTEIN; RNA BINDING PROTEIN; SIP1 PROTEIN, HUMAN; SMN PROTEIN (SPINAL MUSCULAR ATROPHY);

ANIMAL CELL; ARTICLE; CELL DEATH; CELL VIABILITY; CHICKEN; CONTROLLED STUDY; DEGENERATIVE DISEASE; GENE; GENE DISRUPTION; GENE TARGETING; MOTOR NEURON DISEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRE B LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMN GENE; SPINAL MUSCULAR ATROPHY; AMINO ACID SEQUENCE; ANIMAL; BIOLOGICAL MODEL; CELL CULTURE; CELL LINE; CELL SURVIVAL; CHEMISTRY; EXON; FLOW CYTOMETRY; GENE LIBRARY; GENETIC RECOMBINATION; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; PLASMID; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROMOTER REGION; SITE DIRECTED MUTAGENESIS; SOUTHERN BLOTTING; TIME; WESTERN BLOTTING;

ANIMALIA; GALLUS GALLUS;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, SOUTHERN; BLOTTING, WESTERN; CELL DEATH; CELL LINE; CELL SURVIVAL; CELLS, CULTURED; CHICKENS; CONSERVED SEQUENCE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DNA, COMPLEMENTARY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EXONS; FLOW CYTOMETRY; GENE LIBRARY; HUMANS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUSCULAR ATROPHY, SPINAL; MUTAGENESIS, SITE-DIRECTED; NERVE TISSUE PROTEINS; PLASMIDS; PROMOTER REGIONS (GENETICS); RECOMBINATION, GENETIC; RNA-BINDING PROTEINS; TETRACYCLINE; TIME FACTORS; TRANSFECTION;

EID: 0035971112     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009162200     Document Type: Article

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