Catalytic enantioselective synthesis of a novel inhibitor of ceramide trafficking, (1R,3R)-N-(3-hydroxy-1-hydroxymethyl-3-phenylpropyl)-dodecanamide (HPA-12)

Tetrahedron Letters

Volumn 42, Issue 44, 2001, Pages 7863-7865

  Ueno, Masaharu ^a,b   Kitagawa, Hidetoshi ^a,b   Ishitani, Haruro ^a,b   Yasuda, Satoshi ^b,c   Hanada, Kentaro ^b,c   Kobayashi, Sh ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

A novel inhibitor of ceramide trafficking; Asymmetric reaction; HPA 12; Mannich type reaction

Indexed keywords

AMIDE; CERAMIDE; N (3 HYDROXY 1 HYDROXYMETHYL 3 PHENYLPROPYL)DODECANAMIDE; UNCLASSIFIED DRUG; ZIRCONIUM;

ARTICLE; CATALYSIS; CATALYST; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; INTRACELLULAR TRANSPORT; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0035968985     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(01)01658-6     Document Type: Article

References (14)