Epileptiform activity induced by 4-aminopyridine in immature hippocampus

Epilepsy Research

Volumn 2, Issue 3, 1988, Pages 187-195

  Chesnut, Thomas J ^a   Swann, John W ^a  

^a WADSWORTH CENTER   (United States)

Author keywords

4 Aminopyridine; Epileptiform activity; Immature hippocampus; Inhibition

Indexed keywords

4 AMINOPYRIDINE;

ANIMAL CELL; BRAIN SLICE; EPILEPTOGENESIS; HIPPOCAMPUS; IMMATURITY; NEUROTOXICITY; NONHUMAN; RAT;

4-AMINOPYRIDINE; ACTION POTENTIALS; AGE FACTORS; AMINOPYRIDINES; ANIMAL; CONVULSANTS; CONVULSIONS; HIPPOCAMPUS; IN VITRO; RATS;

EID: 0023915149     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/0920-1211(88)90056-3     Document Type: Article

References (46)

1. Characteristics of a slow hyperpolarizing synaptic potential in rat hippocampal pyramidal cells in vitro
2. Specific long-lasting potentiation of synaptic transmission in hippocampal slices
3. Differences between mammalian ventral and dorsal spinal roots in response to blockade of potassium channels during maturation
4. Postsynaptic action of baclofen associated with its antagonism of bicuculline-induced epileptogenesis in hippocampus
5. o(-)APV and kynurenic acid suppress ictal-like activity in penicillin-treated hippocampal slices
6. Ketamine selectively suppresses synchronized afterdischarges in immature hippocampus
7. Enhancement of synaptic transmission by 4-aminopyridine in hippocampal slices of the rat
8. A model for the ionic mechanism of the paroxysmal depolarization shift
9. Electrophysiological mechanisms of kainic acid-induced epileptiform activity in the rat hippocampal slice
10. Spike-wave rhythms in cat cortex induced by parenteral penicillin. II. Cellular features
11. Generalized epilepsy with spike-and-wave discharge: a reinterpretation of its electrographic and clinical manifestations
12. A transient outward current in a mammalian central neuron blocked by 4-aminopyridine
13. Pre- and postsynaptic effects of 4-aminopyridine
14. Giant synaptic potential hypothesis for epileptiform activity
15. Hyperpolarizing potentials in guinea pig hippocampal CA3 neurons
16. Maturation of mammalian myelinated fibers: changes in action-potential characteristics following 4-aminopyridine application
17. Participation of cortical recurrent inhibition in the genesis of spike and wave discharges in feline generalized penicillin epilepsy
18. Alterations of GABA-mediated synaptic transmission in human epilepsy
19. The mode of action of 4-aminopyridine and guanidine on transmitter release from motor nerve terminals
20. Maturational changes in postictal refractoriness and seizure susceptibility in developing rats
21. Increased seizure susceptibility of the immature brain
22. A bicuculline-resistant inhibitory post-synaptic potential in rat hippocampal pyramidal cells in vitro
23. Comparison of the action of baclofen with γ-aminobutyric acid on rat hippocampal pyramidal cells in vitro
24. Synaptic excitation may activate a calcium dependent potassium conductance in hippocampal pyramidal cells
25. Inhibition in ‘epileptic’ neurons
26. Neurophysiology of epilepsy
27. Neuronal activities in epileptogenic foci of immature cortex
28. Non-synaptic mechanisms in epileptogenesis
29. Postsynaptic potentials and spike variations in the feline hippocampus during postnatal ontogenesis
30. Effects of 4-aminopyridine on calcium action potentials and calcium current under voltage clamp in spinal neurons
31. Epileptiform activity induced by changes in extracellular potassium in hippocampus
32. 4-Aminopyridine produces epileptiform activity in hippocampus and enhances synaptic excitation and inhibition
33. Characteristics of CA1 neurons recorded intracellularly in the hippocampal in vitro slice preparation
34. Development of rabbit hippocampus: physiology
35. Intracellular study of human epileptic cortex: in vitro maintenance of epileptiform activity
36. Development of rabbit hippocampus: anatomy
37. Cellular and field potential properties of epileptogenic hippocampal slices
38. Changes in excitatory and inhibitory synaptic potentials leading epileptogenic activity
39. + conductances
40. A transient potassium conductance regulates the excitability of cultured hippocampal and spinal neurons
41. Poisoning with 4-aminopyridine; a report of three cases
42. 4-Aminopyridine and dendrotoxin induce repetitive firing in rat visceral sensory neurons by blocking a slowly inactivating outward current
43. Penicillin-induced epileptogenesis in immature rat CA3 hippocampal pyramidal cells
44. Postnatal development of GABA-mediated synaptic inhibition in rat hippocampus
45. Aminopyridine block of transient potassium current
46. Epileptogenic effects of 4-aminopyridine on hippocampal neurons in vitro