Crystal structure of lactose synthase reveals a large conformational change in its catalytic component, the β1,4-galactosyltransferase-1

Journal of Molecular Biology

Volumn 310, Issue 1, 2001, Pages 205-218

  Ramakrishnan, B ^a,b   Qasba, Pradman K ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

Author keywords

Conformational changes; Crystal structure; Lactose synthase; Modulation; Substrate binding

Indexed keywords

ALPHA LACTALBUMIN; ARGININE; GALACTOSYLTRANSFERASE; GLUCOSE; HISTIDINE; HYDROXYL GROUP; ISOLEUCINE; LACTOSE; LACTOSE SYNTHASE; METAL ION; N ACETYLGLUCOSAMINE; PHENYLALANINE; SUGAR;

ARTICLE; BINDING SITE; CATALYSIS; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME KINETICS; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; HYDROGEN BOND; HYDROPHOBICITY; MILK; NONHUMAN; PRIORITY JOURNAL;

EID: 0035967864     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4757     Document Type: Article

References (35)

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