Solid-phase synthesis of functionalized tropane derivatives via 1,3-dipolar cycloaddition

Tetrahedron Letters

Volumn 42, Issue 22, 2001, Pages 3721-3723

  Caix Haumesser, Sandrine ^a   Hanna, Issam ^a   Lallemand, Jean Yves ^a   Peyronel, Jean François ^b  

^a LABORATOIRE DE SYNTHÈSE ORGANIQUE   (France)

^b SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

3 OXIDOPYRIDINIUM BETAINE; 8 AZABICYCLO[3.2.1]OCTENONE DERIVATIVE; ACID CHLORIDE DERIVATIVE; ALKENE DERIVATIVE; BETAINE DERIVATIVE; CHLORIDE; KETONE DERIVATIVE; POTASSIUM IODIDE; REAGENT; TROPANE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CONFORMATIONAL TRANSITION; CYCLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS; STOICHIOMETRY;

EID: 0035963066     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(01)00565-2     Document Type: Article

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11. 1H NMR of the mixture, after flash column chromatography.
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21. 13C NMR spectra, each of these isomers was found to be a mixture of atropoisomers.
22. -1).
23. 1H NMR spectrum. As for compounds 9 and 10, this product was found to be a mixture of atropoisomers.