Polymorphisms in hypocretin/orexin pathway genes and narcolepsy

Neurology

Volumn 57, Issue 10, 2001, Pages 1896-1899

  Olafsdottir B R ^a   Rye, D B ^b   Scammell, T E ^c   Matheson, J K ^c   Stefansson K ^a   Gulcher, J R ^a  

^a DECODE GENETICS   (Iceland)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; OREXIN;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; GENETIC POLYMORPHISM; HUMAN; NARCOLEPSY; PATHOPHYSIOLOGY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SLEEP DISORDER;

EID: 0035960580     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.57.10.1896     Document Type: Article

References (10)

1. The neurobiology of narcolepsy-cataplexy
2. Narcolepsy
3. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene
4. Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation
5. Reduced number of hypocretin neurons in human narcolepsy
6. Hypocretin levels in sporadic and familial cases of canine narcolepsy
7. Hypocretin (orexin) deficiency in human narcolepsy
8. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains
9. A prepro-orexin gene polymorphism is associated with narcolepsy
10. Using quality measures to facilitate allele calling in high-throughput genotyping