A prepro-orexin gene polymorphism is associated with narcolepsy

Neurology

Volumn 56, Issue 1, 2001, Pages 115-117

  Gencik, M ^a,c   Dahmen, N ^b   Wieczorek, S ^a   Kasten, M ^b   Bierbrauer, J ^a   Anghelescu, I ^b   Szegedi, A ^b   Menezes Saecker, A M ^a   Epplen, J T ^a  

^a ST JOSEF HOSPITAL   (Germany)

^b UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^c RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LEUKOCYTE ANTIGEN; OREXIN; PREPROOREXIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CASE REPORT; ENVIRONMENTAL FACTOR; GENE MUTATION; GENETIC POLYMORPHISM; HALLUCINATION; HUMAN; MALE; NARCOLEPSY; NERVE CONDUCTION; NEUROTRANSMITTER RELEASE; PARASOMNIA; PATHOGENESIS; PRIORITY JOURNAL; SLEEP WAKING CYCLE; TRANSCRIPTION REGULATION;

EID: 0035830409     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.56.1.115     Document Type: Article

References (7)

1. HLA DQB1*0602 is associated with cataplexy in 509 narcoleptic patients
2. Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation
3. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene
4. Hypocretin (orexin) deficiency in human narcolepsy
5. Structure and function of human prepro-orexin gene
6. HLA-DR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours: An alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation
7. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains