Cloning and Characterization of LUN, a Novel RING Finger Protein That Is Highly Expressed in Lung and Specifically Binds to a Palindromic Sequence

Journal of Biological Chemistry

Volumn 276, Issue 17, 2001, Pages 14004-14013

  Chu, Dong ^a   Kakazu, Naoki ^b   Gorrin Rivas, Manuel J ^a   Lu, Hai Ping ^b   Kawata, Mitsuhiro ^b   Abe, Tatsuo ^b   Ueda, Kunihiro ^a   Adachi, Yoshifumi ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOLOGICAL ORGANS; CHROMOSOMES; CLONING; DNA; GENES; RESPIRATORY SYSTEM; RNA; TUMORS; ZINC;

TRANSCRIPTIONAL REGULATORY REGION;

PROTEINS;

CALCIUM ION; CATION; COMPLEMENTARY DNA; DNA; GENOMIC DNA; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; IODINE 125; LUN PROTEIN; MAGNESIUM ION; MANGANESE; MESSENGER RNA; PALINDROMIC DNA; POLYADENYLATED RNA; RING FINGER PROTEIN; TALIN; UNCLASSIFIED DRUG; UVOMORULIN; ZINC ION; CADHERIN; CARRIER PROTEIN; DNA BINDING PROTEIN; FORKHEAD TRANSCRIPTION FACTOR; FOXF2 PROTEIN, HUMAN; LUN PROTEIN, VERTEBRATE; NUCLEAR PROTEIN; TOPORS PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; TUMOR PROTEIN; ZINC;

AMINO ACID SEQUENCE; ARTICLE; CELLULAR DISTRIBUTION; CHROMOSOME 9P; DNA BINDING; GENE; GENE EXPRESSION; GENE LOCUS; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; ISOTOPE LABELING; LUNG CANCER; LUNG CARCINOGENESIS; LUNG NON SMALL CELL CANCER; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN MOTIF; REALLY INTERESTING NEW GENE; RING FINGER MOTIF; TRANSCRIPTION REGULATION; BINDING SITE; BIOSYNTHESIS; CELL NUCLEUS; CHEMISTRY; CHROMOSOME 9; CHROMOSOME MAP; EPITHELIUM; FLUORESCENCE IN SITU HYBRIDIZATION; GENE LIBRARY; GENETIC TRANSFECTION; GENETICS; HELA CELL; HETEROZYGOSITY LOSS; IN SITU HYBRIDIZATION; LUNG; LUNG ALVEOLUS; METABOLISM; MOLECULAR GENETICS; NORTHERN BLOTTING; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING SITES; BLOTTING, NORTHERN; CADHERINS; CARRIER PROTEINS; CATIONS; CELL NUCLEUS; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 9; CLONING, MOLECULAR; DNA; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; EPITHELIUM; FORKHEAD TRANSCRIPTION FACTORS; GENE LIBRARY; GLUTATHIONE TRANSFERASE; HELA CELLS; HUMANS; IN SITU HYBRIDIZATION; IN SITU HYBRIDIZATION, FLUORESCENCE; LOSS OF HETEROZYGOSITY; LUNG; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PULMONARY ALVEOLI; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; TISSUE DISTRIBUTION; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; ZINC;

EID: 0035958081     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010262200     Document Type: Article

References (53)

1. Freemont, P. S. (1993) Ann. N. Y. Acad. Sci. 684, 174-192
2. Saurin, A. J., Borden, K. L. B., Boddy, M. N., and Freemont, P. S. (1996) Trends Biochem. Sci. 21, 208-214
3. Barlow, P. N., Luisi, B., Milner, A., Elliott, M., and Everett, R. (1994) J. Mol. Biol. 237, 201-211
4. Everett, R. D., Barlow, P., Milner, A., Luisi, B., Orr, A., Hope, G., and Lyon, D. (1993) J. Mol. Biol. 234, 1038-1047
5. Borden, K. L. B., Boddy, M. N., Lally, J., O'Reilly, N. J., Martin, S., Howe, K., Solomon, E., and Freemont, P. S. (1995) EMBO J. 14, 1532-1541
6. Tagawa, M., Sakamoto, T., Shigemoto, K., Matsubara, H., Tamura, Y., Ito, T., Nakamura, I., Okitsu, A., Imai, K., and Taniguchi, M. (1990) J. Biol. Chem. 265, 20021-20026
7. Kanno, M., Hasegawa, M., Ishida, A., Isono, K., and Taniguchi, M. (1995) EMBO J. 14, 5672-5678
8. Lovering, R., Hanson, I. M., Borden, K. L. B., Martin, S., O'Reilly, N. J., Evan, G. I., Rahman, D., Pappin, D. J. C., Trowsdale, J., and Freemont, P. S. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 2112-2116
9. Joazeiro, C. A., Wing, S. S., Huang, H., Leverson, J. D., Hunter, T., and Liu, Y. C. (1999) Science 286, 309-312
10. Lorick, K. L., Jensen, J. P., Fang, S., Ong, A. M., Hatakeyama, S., and Weissman, A. M. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 11364-11369
11. Miki, Y., Swensen, J., Shattuck-Eidens, D., Futreal, P. A., Harshman, K., Tavtigian, S., Liu, Q., Cochran, C., Bennett, L. M., Ding, W., Bell, L., Rosenthal, J., Hussey, C., Tran, T., McClure, M., Frye, C., Hattier, T., Phelps, R., Haugen-Strano, A., Katcher, H., Yakumo, K., Gholami, Z., Shaffer, D., Stone, S., Bayer, S., Wray, C., Bogden, R., Dayananth, P., Ward, J., Tonin, P., Narod, S., Bristow, P. K., Norris, F. H., Helvering, L., Morrison, P., Rosteck, P., Lai, M., Barrett, J. C., Lewis, C., Neuhausen, S., Cannon-Albright, L., Goldgar, D., Wiseman, R., Kamb, A., and Skolnick, M. H. (1994) Science 266, 66-71
12. Goddard, A. D., Borrow, J., Freemont, P. S., and Solomon, E. (1991) Science 254, 1371-1374
13. Kakizuka, A., Miller, W. H., Jr., Umesono, K., Warrell, R. P., Jr., Frankel, S. R., Murty, V. V. V. S., Dmitrovsky, E., and Evans, R. M. (1991) Cell 66, 663-674
14. Hasegawa, N., Iwashita, T., Asai, N., Murakami, H., Iwata, Y., Isomura, T., Goto, H., Hayakawa, T., and Takahashi, M. (1996) Biochem. Biophys. Res. Commun. 225, 627-631
15. Blake, T. J., Heath, K. G., and Langdon, W. Y. (1993) EMBO J. 12, 2017-2026
16. von Lohuizen, M., Verbeek, S., Scheijen, B., Wientjens, E., van der Gulden, H., and Berns, A. (1991) Cell 65, 737-752
17. Haupt, Y., Alexander, W. S., Barri, G., Peter Klinken, S., and Adams, J. M. (1991) Cell 65, 753-763
18. Goebl, M. G. (1991) Cell 66, 623
19. Takahashi, H., Behbakht, K., McGovern, P. E., Chiu, H. C., Couch, F. J., Weber, B. L., Friedman, L. S., King, M. C., Furusato, M., LiVolsi, V. A., Menzin, A. W., Liu, P. C., Benjamin, I., Morgan, M. A., King, S. A., Rebane, B. A., Cardonick, A., Mikuta, J. J., Rubin, S. C., and Boyd, J. (1995) Cancer Res. 55, 2998-3002
20. Inazawa, J., Sasaki, H., Nagura, K., Kakazu, N., Abe, T., and Sasaki, T. (1996) Hum. Genet. 98, 508-510
21. Inazawa, J., Ariyama, T., Abe, T., Druck, T., Ohta, M., Huebner, K., Yanagisawa, J., Reed, J. C., and Sato, T. (1996) Genomics 31, 240-242
22. Adachi, Y., Kitahara-Ozawa, A., Sugamura, K., Lee, W. J., Yodoi, J., Maki, M., Murachi, T., and Hatanaka, M. (1992) J. Biol. Chem. 267, 19373-19378
23. Morimoto, M., Morita, N., Ozawa, H., Yokoyama, K., and Kawata, M. (1996) Neurosci. Res. 26, 235-269
24. Kozak, M. (1989) J. Cell Biol. 108, 229-241
25. Zhou, R., Wen, H., and Ao, S. Z. (1999) Gene 235, 93-101
26. Haluska, P. Jr., Saleem, A., Rasheed, Z., Ahmed, F., Su, E. W., Liu, L. F., and Rubin, E. H. (1999) Nucleic Acids Res. 27, 2538-2544
27. Rodriguez, M. S., Desterro, J. M. P., Lain, S., Midgley, C. A., Lane, D. P., and Hay, R. T. (1999) EMBO J. 18, 6455-6461
28. Desterro, J. M. P., Rodriguez, M. S., and Hay, R. T. (1998) Mol. Cell 2, 233-239
29. Kastner, P., Perez, A., Lutz, Y., Rochette-Egly, C., Gaub, M. P., Durand, B., Lanotte, M., Berger, R., and Chambon, P. (1992) EMBO J. 11, 629-642
30. Patarca, R., Schwartz, J., Singh, R. P., Kong, Q. T., Murphy, E., Anderson, Y., Sheng, F. Y., Singh, P., Johnson, K. A., Guarnagia, S. M., Durfee, T., Blattner, F., and Cantor, H. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 2733-2737
31. Everett, R. D., and Maul, G. G. (1994) EMBO J. 31, 5062-5069
32. Spanopoulou, E., Zaitseva, F., Wang, F. H., Santagata, S., Baltimore, D., and Panayotou, G. (1996) Cell 87, 263-276
33. Mo, X., Bailin, T., and Sadofsky, M. J. (1999) J. Biol. Chem. 274, 7025-7031
34. Lo, K., Landau, N. R., and Smale, S. T. (1991) Mol. Cell. Biol. 11, 5229-5243
35. Molnar, A., and Georgopoulos, K. (1994) Mol. Cell. Biol. 14, 8292-8303
36. Driever, W., and Nusslein-Volhard, C. (1989) Nature 337, 138-143
37. Driever, W., Thoma, G., and Nusslein-Volhard, C. (1989) Nature 340, 363-367
38. Chen, Y., and Gill, G. N. (1996) J. Biol. Chem. 271, 5181-5188
39. Yoshiura, K., Kanai, Y., Ochiai, A., Shimoyama, Y., Sugimura, T., and Hirohashi, S.(1995) Proc. Natl. Acad. Sci. U. S. A. 92, 7416-7419
40. Jones, J. S., Weber, S., and Prakash, L. (1988) Nucleic Acids Res. 16, 7119-7131
41. Schatz, D. G., Oettinger, M. A., and Baltimore, D. (1989) Cell 59, 1035-1048
42. Christofori, G., and Semb, H. (1999) Trends Biochem. Sci. 24, 73-76
43. Sommers, C. L., Thompson, E. W., Torri, J. A., Kemler, R., Gelmann, E. P., and Byers, S. W. (1991) Cell Growth Differ. 2, 365-372
44. Oka, H., Shiozaki, H., Kobayashi, K., Inoue, M., Tahara, H., Kobayashi, T., Takatsuka, Y., Mastuyoshi, N., Hirano, S., Takeichi, M., and Mori, T. (1993) Cancer Res. 53, 1696-1701
45. Goldmann, W. H. (2000) Biochem. Biophys. Res. Commun. 271, 553-557
46. Albiges-Rizo, C., Frachet, P., and Block, M. R. (1995) J. Cell Sci. 108, 3317-3329
47. Blank, V., and Andrews, N. C, (1997) Trends Biochem. Sci. 22, 437-441
48. Kataoka, K., Noda, M., and Nishizawa, M. (1994) Mol. Cell. Biol. 14, 700-712
49. Glover, J. N. M., and Harrison, S. C. (1995) Nature 373, 257-261
50. Ellenberger, T. E., Brandl, C. J., Struhl, K., and Harrison, S. C. (1992) Cell 71, 1223-1237
51. Mao, Y., Sun, M., Desai, S. D., and Liu, L. F. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 4046-4051
52. Kim, S. K., Ro, J. Y., Kemp, B. L., Lee, J. S., Kwon, T. J., Fong, K. M., Sekido, Y., Minna, J. D., Hong, W. K., and Mao, L. (1997) Cancer Res. 57, 400-403
53. Bohm, M., Totzeck, B., and Wieland, I. (1994) Clin. Exp. Metastasis 12, 55-62