Id1 expression is associated with histological grade and invasive behavior in endometrial carcinoma

Cancer Letters

Volumn 165, Issue 2, 2001, Pages 185-193

  Takai, Noriyuki ^a   Miyazaki, Tami ^a   Fujisawa, Kayo ^a   Nasu, Kaei ^a   Miyakawa, Isao ^a  

^a OITA UNIVERSITY   (Japan)

Author keywords

Endometrial carcinoma; Histological grade; Id1; Myometrial invasion

Indexed keywords

HELIX LOOP HELIX PROTEIN; INHIBITOR OF DIFFERENTIATION 1; UNCLASSIFIED DRUG;

ARTICLE; CANCER GRADING; CANCER INVASION; CANCER STAGING; CARCINOGENESIS; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOMETRIUM; ENDOMETRIUM CARCINOMA; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INFLAMMATORY CELL; MALIGNANT NEOPLASTIC DISEASE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ADULT; CARCINOMA; CELL DIVISION; DNA-BINDING PROTEINS; ENDOMETRIAL NEOPLASMS; ENDOMETRIUM; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INHIBITOR OF DIFFERENTIATION PROTEIN 1; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; REPRESSOR PROTEINS; TRANSCRIPTION FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 0035953852     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(01)00433-5     Document Type: Article

References (36)

1. The protein Id: A negative regulator of helix-loop-helix DNA binding proteins
2. Structure and function of helix-loop-helix proteins
3. The expression pattern of Id4, a novel dominant negative helix-loop-helix protein, is distinct from Id1, Id2 and Id3
4. Expression of the Id family helix-loop-helix regulators during growth and development in the hematopoietic system
5. Cdk2-dependent phosphorylation of Id2 modulates activity of E2A-related transcription factors
6. Expression of c-Ets1 is associated with malignant potential in endometrial carcinoma
7. Polo-like kinase (PLK) expression in normal human endometrium during the menstrual cycle
8. Id-1 and Id-2 are overexpressed in pancreatic cancer and in dysplastic lesions in chronic pancreatitis
9. Id gene expression as a key mediator of tumor cell biology
10. Coupling of cell growth control and apoptosis functions of Id proteins
11. Nucleotide sequence of the cDNA encoding human helix-loop-helix Id-1 protein: Identification of functionally conserved residues common to Id proteins
12. A human Id-like helix-loop-helix protein expressed during early development
13. Mutually exclusive expression of a helix-loop-helix gene and N-myc in human neuroblastomas and in normal development
14. Molecular cloning of ID4, a novel dominant negative helix-loop-helix human gene on chromosome 6p21.3-p22
15. Id-related genes encoding helix-loop-helix proteins are required for G1 progression and are repressed in senescent human fibroblasts
16. Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins
17. An Id-related helix-loop-helix protein encoded by a growth factor-inducible gene
18. Inhibition of myeloid differentiation by the helix-loop-helix protein Id
19. Suppression of mammary epithelial cell differentiation by helix-loop-helix protein Id-1
20. Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increase in the levels of epidermal growth factor and transforming growth factor α
21. Regulation of the expression of cyclin-dependent kinase inhibitor p21 by E2A and Id proteins
22. Regulation of Id3 cell cycle function by Cdk-2-dependent phosphorylation
23. Forced expression of Id-1 in the adult mouse small intestinal epithelium is associated with development of adenomas
24. The gene for the helix-loop-helix protein, Id, is specifically expressed in neural precursors
25. Expression of helix-loop-helix factor Id-1 is dependent on the hepatocyte proliferation and differentiation status in rat liver and in primary culture
26. Id gene expression and its suppression by 1,25-dihydroxyvitamin D3 in rat osteoblastic osteosarcoma cells
27. Repression of immunoglobulin enhancers by the helix-loop-helix protein Id: Implications for B-lymphoid-cell development
28. A novel pathway for mammary epithelial cell invasion induced by the helix-loop-helix protein Id-1
29. The helix-loop-helix protein Id2 is overexpressed in human pancreatic cancer
30. A role for Id-1 in the aggressive phenotype and steroid hormone response of human breast cancer cells
31. Id gene expression during development and molecular cloning of the human Id-1 gene
32. Id genes encoding inhibitors of transcription are expressed during in vitro astrocyte differentiation and in cell lines derived from astrocytic tumors
33. The helix-loop-helix transcription factors Id1 and Id3 have a functional role in control of cell division in human normal and neoplastic chondrocytes
34. Increased incidence of matrix metalloproteinases in urine of cancer patients
35. Immortalization of primary human keratinocytes by the helix-loop-helix protein, Id-1
36. The helix-loop-helix protein Id1 and retinoblastoma protein binding mutant of SV40 T antigen synergize to reactivate DNA synthesis in senescent human fibroblasts