Acceleration of thrombomodulin gene transcription by retinoic acid. Retinoic acid receptors and Sp1 regulate the promoter activity through interactions with two different sequences in the 5′-flanking region of human gene

Journal of Biological Chemistry

Volumn 276, Issue 4, 2001, Pages 2440-2450

  Horie, Shuichi ^b   Ishii, Hidemi ^a   Matsumoto, Fumiko ^c   Kusano, Masao ^c   Kizaki, Keiichiro ^c   Matsuda, Juzo ^c   Kazama, Mutsuyoshi ^c  

^a SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

^b TEIKYO UNIVERSITY   (Japan)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BIOASSAY; CELLS; DIMERS; DNA; ELECTRON MOBILITY; GENETIC ENGINEERING; MUTAGENESIS; PROTEINS; REACTION KINETICS;

GENE TRANSCRIPTION;

BIOCHEMISTRY;

DIMER; PREGNANCY SPECIFIC BETA1 GLYCOPROTEIN; RETINOIC ACID; RETINOIC ACID RECEPTOR ALPHA; RETINOIC ACID RECEPTOR BETA; RETINOIC ACID RECEPTOR GAMMA; RETINOID X RECEPTOR; RETINOID X RECEPTOR ALPHA; THROMBOMODULIN; UNCLASSIFIED DRUG; MESSENGER RNA; NUCLEAR PROTEIN; RETINOIC ACID RECEPTOR; TRANSCRIPTION FACTOR SP1;

5' UNTRANSLATED REGION; ARTICLE; BINDING SITE; CELL LINE; CELL LYSATE; CONCENTRATION RESPONSE; DNA FLANKING REGION; GEL MOBILITY SHIFT ASSAY; GENE MUTATION; HUMAN; HUMAN CELL; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RETICULOCYTE; TANDEM REPEAT; TRANSCRIPTION REGULATION; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; DIMERIZATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PANCREAS; PHOSPHORYLATION; STEREOISOMERISM; TRANSACTIVATION; UPREGULATION;

BINDING SITES; CELLS, CULTURED; DIMERIZATION; HUMANS; NUCLEAR PROTEINS; PANCREAS; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RECEPTORS, RETINOIC ACID; RNA, MESSENGER; SP1 TRANSCRIPTION FACTOR; STEREOISOMERISM; THROMBOMODULIN; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION, GENETIC; TRETINOIN; UP-REGULATION;

EID: 0035951885     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M004942200     Document Type: Article

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