Downregulation of transforming growth factor-γ1 in interferon-β1a-treated MS patients

Neurology

Volumn 57, Issue 6, 2001, Pages 1132-1134

  Lunemann J D ^a   Aktas, O ^a   Gniadek, P ^a   Zschenderlein, R ^a   Zipp, F ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1A INTERFERON; INTERLEUKIN 10; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; AGED; ARTICLE; BLOOD LEVEL; DOWN REGULATION; DRUG EFFICACY; DRUG MECHANISM; FEMALE; HUMAN; IMMUNOREGULATION; MAJOR CLINICAL STUDY; MALE; MONONUCLEAR CELL; MULTIPLE SCLEROSIS; PRIORITY JOURNAL;

EID: 0035949745     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.57.6.1132     Document Type: Article

References (10)

1. Regulation of immune response by TGF-β
2. Tumor necrosis factor-α mRNA expression in patients with relapsing-remitting multiple sclerosis is associated with disease activity
3. Immunomodulatory effects of interferon-β-1b in vivo: Induction of the expression of transforming growth factor-β1 and its receptor type II
4. The inhibitory effects of transforming growth factor-β-1 (TGF-β1) in autoimmune diseases
5. Increased transforming growth factor-β, interleukin-4, and interferon-γ in multiple sclerosis
6. Phase 1 trial of transforming growth factor beta 2 in chronic progressive MS
7. Long-term effect of IFN-β1b treatment on the spontaneous and induced expression of IL-10 and TGFβ1 in MS patients
8. Interferon beta induces interleukin-10 expression: Relevance to multiple sclerosis
9. In vivo effects of interferon β-1a on immunosuppressive cytokines in multiple sclerosis
10. Transforming growth factor β1 inhibits Fas ligand expression and subsequent activation-induced cell death in T cells via down regulation of c-myc