Photoactivation of DNA thiobases as a potential novel therapeutic option

Current Biology

Volumn 11, Issue 14, 2001, Pages 1142-1146

  Massey, Andrew ^a   Xu, Yao Zhong ^b   Karran, Peter ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0035943008     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00272-X     Document Type: Article

References (21)

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3. Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine
4. Thionucleobases as intrinsic photoaffinity probes of nucleic acid structure and nucleic acid-protein interactions
5. Combined mismatch and nucleotide excision repair defects in a human cell line: Mismatch repair processes methylation but not UV-or ionizing-radiation-induced DNA damage
6. Synthesis and in vitro evaluation of some modified 4-thiopyrimidine nucleosides for prevention or reversal of AIDS-associated neurological disorders
7. Mismatch repair and p53 independently affect sensitivity to N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea
8. Genetic consequences of tolerance to alkylation DNA damage in mammalian cells
9. Hypersensitivity of skin fibroblasts from patients with chronic actinic dermatitis to ultraviolet B (UVB), UVA and superoxide radical
10. Differential behaviors toward ultraviolet A and B radiation of fibroblasts and keratinocytes from normal and DNA-repair-deficient patients
11. Increased somatic recombination in methylation tolerant cells with defective mismatch repair
12. Methylation of 4-thio-2′-deoxyuridylate by thymidylate synthetase
13. Photoinactivation (365nm) of vaccinia and herpes simplex viruses induced by a new built-in DNA photosensitizer: 4-thiothymidine
14. Preparation of oligoribonucleotides containing 4-thiouridine using Fpmp chemistry. Photocrosslinking to RNA binding proteins using 350 nm irradiation
15. Photochemistry and the nucleic acids
16. Synthesis and characterisation of oligodeoxynucleotides containing thio analogues of (6-4) pyrimidine-pyrimidone photo-dimers
17. Unique DNA repair properties of a xeroderma pigmentosum revertant
18. Hammerhead ribozyme tertiary folding: Intrinsic photolabelling studies
19. Thymidine kinase expression. A marker for malignant cells
20. Simple synthesis of 4-thiothymidine, 4-thiouridine and 6-thio-2′-deoxyguanosine