The DBP transcriptional activation domain is highly homologous to that of HLF and TEF and is not responsible for the tissue type-specific transcriptional activity of DBP

Gene

Volumn 263, Issue 1-2, 2001, Pages 239-245

  Li, Shaobing ^a   Hunger, Stephen P ^a,b  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

Basic leucine zipper proteins; Proline and acidic amino acid rich proteins; Transcription factor

Indexed keywords

ALBUMIN D ELEMENT BINDING PROTEIN; AMINO ACID; HEPATIC LEUKEMIA FACTOR; HYBRID PROTEIN; LEUCINE ZIPPER PROTEIN; THYROTROPH EMBRYONIC FACTOR; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL SPECIFICITY; CELL STRAIN 3T3; CELL STRAIN HEPG2; CONTROLLED STUDY; GENE ACTIVATION; GENE CONTROL; GENE DELETION; GENE EXPRESSION; GENE FUNCTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SEQUENCE HOMOLOGY; TRANSCRIPTION REGULATION;

3T3 CELLS; AMINO ACID SEQUENCE; ANIMALS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; BINDING SITES; CHLORAMPHENICOL O-ACETYLTRANSFERASE; DNA, RECOMBINANT; DNA-BINDING PROTEINS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PLASMIDS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SEQUENCE DELETION; SEQUENCE HOMOLOGY, AMINO ACID; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; ZEBRAFISH PROTEINS;

DANIO RERIO; MAMMALIA; RICKETTSIA SP. PAR;

EID: 0035941481     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(00)00565-5     Document Type: Article

References (24)

1. Alternative promoter usage and splicing options result in the differential expression of mRNAs encoding four isoforms of chicken VBP, a member of the PAR subfamily of bZIP transcription factors
2. TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins
3. The rat hepatic leukemia factor (HLF) gene encodes two transcriptional activators with distinct circadian rhythms, tissue distributions and target preferences
4. DNA-binding specificity of PAR and C/EBP leucine zipper proteins: A single amino acid substitution in the C/EBP DNA-binding domain confers PAR-like specificity to C/EBP
5. The two PAR leucine zipper proteins. TEF and DBP, display similar circadian and tissue-specific expression, but have different target promoter preferences
6. DNA-binding specificity of the PAR basic leucine zipper protein VBP partially overlaps those of the C/EBP and CREB/ATF families and is influenced by domains that flank the core basic region
7. DNA-binding and transcriptional regulatory properties of hepatic leukemia factor (HLF) and the t(17;19) acute lymphoblastic leukemia chimera E2A-HLF
8. The proto-oncogene HLF and the related basic leucine zipper protein TEF display highly similar DNA-binding and transcriptional regulatory properties
9. Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia
10. Transcription factors 1: bZIP proteins
11. Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia
12. DNA-binding specificity and trans-activating potential of the leukemia-associated E2A-hepatic leukemia factor fusion protein
13. Chicken vitellogenin gene-binding protein, a leucine zipper transcription factor that binds to an important control element in the chicken vitellogenin II promoter, is related to rat DBP
14. Chromosomal localization and cDNA cloning of the human DBP and TEF genes
15. D-site binding protein transactivation requires the proline- and acid-rich domain and involves the coactivator p300
16. Circadian transcription of the cholesterol 7 alpha hydroxylase gene may involve the liver-enriched bZIP protein DBP
17. Multiple, functional DBP sites on the promoter of the cholesterol 7 alpha-hydroxylase P450 gene, CYP7. Proposed role in diurnal regulation of liver gene expression
18. Transcription activation by the adenovirus E1a protein
19. PDP1, a novel Drosophila PAR domain bZIP transcription factor expressed in developing mesoderm, endoderm and ectoderm, is a transcriptional regulator of somatic muscle genes
20. CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements
21. DBP, a liver-enriched transcriptional activator, is expressed late in ontogeny and its tissue specificity is determined posttranscriptionally
22. Expression of the liver-enriched transcriptional activator protein DBP follows a stringent circadian rhythm
23. Cloning and characterization of two isoforms of the zebrafish thyrotroph embryonic factor (tef alpha and tef beta)
24. Role of the liver-enriched transcription factor DBP in expression of the cytochrome P450 CYP2C6 gene