Adrenalectomy causes loss of zinc ions in zinc-enriched (ZEN) terminals and decreases seizure-induced neuronal death

Brain Research

Volumn 895, Issue 1-2, 2001, Pages 25-32

  Suh, Sang Won ^a,b   Jo, Seung Mook ^a,c   Vajda, Zsolt ^a   Danscher, Gorm ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^c Hallym University   (South Korea)

Author keywords

Adrenalectomy; AMG; Glucocorticoid; Hippocampus; Seizure; TSQ; Zinc

Indexed keywords

KAINIC ACID; TOLUENESULFONAMIDE DERIVATIVE; TOLUENESULFONAMIDE QUINOLINE; UNCLASSIFIED DRUG; ZINC ION; ZINC SULFIDE;

ADRENALECTOMY; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOMETALLOGRAPHY; CONTROLLED STUDY; DISEASE DURATION; FLUOROMETRY; HEAD INJURY; HIPPOCAMPUS; HYDROCORTISONE BLOOD LEVEL; LATENT PERIOD; MALE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE; SYNAPSE VESICLE;

ADRENALECTOMY; ANIMALS; BRAIN; CELL DEATH; GLUCOCORTICOIDS; HIPPOCAMPUS; HYDROCORTISONE; MALE; NERVE DEGENERATION; PRESYNAPTIC TERMINALS; PYRAMIDAL CELLS; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES; STRESS; SYNAPTIC VESICLES; ZINC;

EID: 0035937517     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)01996-5     Document Type: Article

References (53)

1. Depletion of intracellular zinc induces protein synthesis-dependent neuronal apoptosis in mouse cortical culture
2. 2+ from brain tissue during activity
3. Morphologische Veränderungen im Diencephalon und Telencephalon nach Storungen des regelkreises Adenohypophyse-Nebennierenrinde. III Ergebnisse beim Meerschweinchen nach Verabreichung von Cortisone und Hydrocortisone
4. Primary and secondary cerebral lesions produced by kainic acid injections in the rat
5. Adrenalectomy increases bicuculline-induced seizure sensitivity in long-sleep and short-sleep mice
6. Serum cortisol in adrenal hirsutism as estimated by five different methods
7. Seizures and neuronal damage in mice lacking vesicular zinc
8. The dithizone, Timm's sulphide silver and the selenium methods demonstrate a chelatable pool of zinc in CNS. A proton activation (PIXE) analysis of carbon tetrachloride extracts from rat brains and spinal cords intravitally treated with dithizone
9. Autometallographic silver enhancement of zinc sulfide crystals created in cryostat sections from human brain biopsies. A new technique that makes it feasible to demonstrate zinc ions in tissue sections from biopsies and early autopsy material
10. Corticosterone impairs hippocampal neuronal calcium regulation-possible mediating mechanisms
11. Zinc-rich synaptic boutons in human temporal cortex biopsies
12. Neurobiology of zinc and zinc-containing neurons
13. A quinoline fluorescence method for visualizing and assaying the histochemically reactive zinc (bouton zinc) in the brain
14. Loss of zinc staining from hippocampal mossy fibers during kainic acid induced seizures: A histofluorescence study
15. Translocation of zinc may contribute to seizure-induced death of neurons
16. Stress-induced release of zinc observed by TSQ fluorescence imaging
17. Zinc content in discrete hippocampal and amygdaloid areas of the epilepsy (El) mouse and normal mice
18. Neuroprotection by melatonin from kainate-induced excitotoxicity in rats
19. Dentate granule cells are essential for kainic acid-induced wet dog shakes but not for seizures
20. Stimulation-induced uptake and release of zinc in hippocampal slices
21. Restraint stress-induced changes in endogenous zinc release from the rat hippocampus
22. The role of zinc in selective neuronal death following transient global cerebral ischemia
23. Hippocampal aging and adrenocorticoids: A quantitative correlation
24. Accumulation of zinc in degenerating hippocampal neurons of ZnT3-null mice after seizures: Evidence against synaptic vesicle origin
25. Effect of metal chelating agents on the direct and seizure-related neuronal death induced by zinc and kainic acid
26. Noncompetitive inhibition of gamma-aminobutyric acid A channels by zinc
27. Selective retention of corticosterone by limbic structures in rat brain
28. Proconvulsant action of diethyldithiocarbamate in stimulation of the perforant path
29. Diethyldithiocarbamate and dithizone augment the toxicity of kainic acid
30. Regulation of ischemic hippocampal damage in the gerbil: Adrenalectomy alters the rate of CA1 cell disappearance
31. Effects of subcutaneous injections of zinc chloride on seizures induced by noise and by kainic acid
32. Zinc selectively blocks the action of N-methyl-D-aspartate on cortical neurons
33. A mechanism for glucocorticoid toxicity in the hippocampus: Increased neuronal vulnerability to metabolic insults
34. Glucocorticoid toxicity in the hippocampus: Temporal aspects of synergy with kainic acid
35. Glucocorticoids potentiate ischemic injury to neurons: Therapeutic implication
36. Hippocampal atrophy in recurrent major depression
37. A selective loss of hippocampal mossy fiber Timm stain accompanies granule cell seizure activity induced by perforant path stimulation
38. Selective loss of hippocampal granule cells in the mature rat brain after adrenalectomy
39. Electron microscopic analysis of adrenalectomy-induced hippocampal granule cell degeneration in the rat: Apoptosis in the adult central nervous system
40. A novel effect of zinc on the lobster muscle GABA receptor
41. Hippocampal vulnerability to stress and aging: Possible role of neurotrophic factors
42. Corticosterone replacement restores normal morphological features to the hippocampal dendrites, axons and synapses of adrenalectomized rats
43. Chemical adrenalectomy reduces hippocampal damage induced by kainic acid
44. Extracellular zinc mediates selective neuronal death in hippocampus and amygdala following kainate-induced seizure
45. Evidence that release of zinc kills neurons after mechanical trauma to the brain
46. Rapid disappearance of zinc positive terminals in focal brain ischemia
47. Neuropsychiatric aspects of Cushing's syndrome
48. Possible role of zinc in the selective degeneration of dentate hilar neurons after cerebral ischemia in the adult rat
49. Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons
50. 2+ antagonize NMDA and GABA responses of hippocampal neurons
51. A physiological role for endogenous zinc in rat hippocampal synaptic neurotransmission
52. Interaction of zinc with ionotropic and metabotropic glutamate receptors in rat hippocampal slices
53. Brief exposure to zinc is neurotoxic to cortical neurons