Non-clonability correlates with genomic instability: A case study of a unique DNA region

Journal of Molecular Biology

Volumn 307, Issue 2, 2001, Pages 481-486

  Razin, Sergey V ^a,b   Ioudinkova, Elena S ^a,b   Trifonov, Edward N ^c,d   Scherrer, Klaus ^a  

^a INSTITUT JACQUES MONOD   (France)

^b INSTITUTE OF GENE BIOLOGY   (Russian Federation)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^d UNIVERSITY OF HAIFA   (Israel)

Author keywords

"unclonable" DNA; Genomic instability; Globin genes; Kinkable dinucleotide steps; Nuclear matrix

Indexed keywords

DINUCLEOTIDE; DNA; DNA FRAGMENT; GLOBIN;

ARTICLE; CHROMOSOME; DNA SEQUENCE; ESCHERICHIA COLI; EUKARYOTE; GENETIC POLYMORPHISM; GENOME; NONHUMAN; PRIORITY JOURNAL; PROKARYOTE; TRANSPOSON;

BACTERIA (MICROORGANISMS); EUKARYOTA; GALLUS GALLUS; PROKARYOTA;

EID: 0035937249     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.4372     Document Type: Article

References (23)

1. Mechanisms of transposition in bacteria
2. Isochores and the evolutionary genomics of vertebrates
3. Chicken hematopoietic cells transformed by seven strains of defective avian leukemia viruses display three distinct phenotypes of differentiation
4. Human growth hormone receptor: Cloning and expression of the full-length complementary DNA after site-directed inactivation of a criptic bacterial promoter
5. Nuclear matrix protein ARBP recognizes a novel DNA sequence motif with high affinity
6. Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites
7. The presence of sequence-specific protein binding site correlate with replication activity and matrix binding in a 1.7 kb-long DNA fragment of the chicken α-globin gene domain
8. Analysis of the closely linked adult chicken α-globin genes in recombinant DNAs
9. Mapping of structural and transcription-related matrix attachment sites in the α-globin gene domain of avian erythroblasts and erythrocytes
10. Mammalian retroposons integrate at kinkable DNA sites
11. Tandem repeats 3′ of the IGHA genes in the human immunoglobulin heavy chain gene cluster
12. Sequence-dependent kinks induced in curved DNA
13. A + T-rich linkers define functional domains en eukaryotic DNA
14. Cloning of the newt Pleurodeles waltlii chromosomal DNA
15. Chromosomal DNA loops may constitute basic units of the eukaryotic genome organization and evolution
16. Extensive methylation of a part of the CpG island located 3.0-4.5 kbp upstream to the chicken alpha-globin gene cluster may contribute to silencing the globin genes in non-erythroid cells
17. Tn5: A molecular window on transposition
18. Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8)
19. Crystal structure of a CAP-DNA complex: The DNA is bent by 90 degrees
20. Structure of the murine lactotransferrin gene is similar to the structure of other transferrin-encoding genes and shares a putative regulatory region with the murine myeloperoxidase gene
21. The expected fraction of clonable genomic DNA
22. The sequence of a nearly unclonable 22.8 kb segment of the left arm chromosome VII from Saccharomyces cerevisiae reveals ARO2, RPL9A, TIP1, MRF1 genes and six new open reading frames
23. Propagation of some human DNA sequences in bacteriophage 1 vectors requires mutant Escherichia coli hosts