Orf135 from Escherichia coli Is a Nudix Hydrolase Specific for CTP, dCTP, and 5-Methyl-dCTP

Journal of Biological Chemistry

Volumn 276, Issue 8, 2001, Pages 5421-5426

  O'Handley, Suzanne F ^a,b   Dunn, Christopher A ^a   Bessman, Maurice J ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b UNIVERSITY OF RICHMOND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CATALYSIS; CLONING; ENZYMES; ESCHERICHIA COLI; GENES; LIPIDS; PH EFFECTS; PHOSPHATES; SUBSTRATES;

DIVALENT METAL CATIONS;

BIOCHEMISTRY;

5 METHYLDEOXYCYTIDINE TRIPHOSPHATE; CYTIDINE TRIPHOSPHATE; DEOXYCYTIDINE TRIPHOSPHATE; HYDROLASE; INORGANIC PYROPHOSPHATASE; MAGNESIUM; NUCLEOSIDE TRIPHOSPHATE; NUDIX HYDROLASE; PROTEIN ORF135; PYRIMIDINE DEOXYNUCLEOSIDE TRIPHOSPHATE; PYRIMIDINE NUCLEOSIDE DERIVATIVE; PYRIMIDINE NUCLEOSIDE TRIPHOSPHATE; UNCLASSIFIED DRUG; 2'-DEOXYCYTIDINE 5'-TRIPHOSPHATE; 5-METHYLDEOXYCYTIDINE TRIPHOSPHATE; DEOXYCYTIDINE PHOSPHATE; NUDIX HYDROLASE ORF135; RECOMBINANT PROTEIN;

ALKALINITY; ARTICLE; CATALYSIS; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENE OVEREXPRESSION; LIPOGENESIS; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; OPTICAL ROTATION; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FUNCTION; PYRIMIDINE SYNTHESIS; AMINO ACID SEQUENCE; COMPARATIVE STUDY; ENZYMOLOGY; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; MULTIGENE FAMILY; SEQUENCE HOMOLOGY;

ESCHERICHIA COLI; FELIS CATUS;

AMINO ACID SEQUENCE; CLONING, MOLECULAR; CYTIDINE TRIPHOSPHATE; DEOXYCYTOSINE NUCLEOTIDES; ESCHERICHIA COLI; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PYROPHOSPHATASES; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

EID: 0035937181     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M004100200     Document Type: Article

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