Letter to the Editor: Adrenal tumors in BRCA1/BRCA2 mutation carriers [1]

American Journal of Medical Genetics

Volumn 98, Issue 3, 2001, Pages 277-279

  Barak, Frieda ^a   Shiri Svredlov, Ronit ^b   Sade, Revital Bruchim Bar ^a   Kruglikova, Anna ^c   Friedman, Eitan ^b   Ben Dor, David ^b   Goldberg, Iris ^b  

^a BARZILAI MEDICAL CENTER   (Israel)

^b GERTNER INSTITUTE FOR EPIDEMIOLOGY AND HEALTH POLICY RESEARCH   (Israel)

^c SHEBA MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; DNA; TRANSCRIPTION FACTOR; TUMOR PROTEIN;

ADRENAL TUMOR; ADULT; CASE REPORT; FEMALE; GENE MUTATION; GENETIC RISK; GERM LINE; HETEROZYGOTE DETECTION; HUMAN; JEW; LETTER; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; CHEMISTRY; GENE DELETION; GENE EXPRESSION REGULATION; GENETICS; HETEROZYGOTE; MIDDLE AGED; MUTATION; NUCLEOTIDE SEQUENCE; PATHOLOGY; PHEOCHROMOCYTOMA;

ADRENAL GLAND NEOPLASMS; BRCA1 PROTEIN; BRCA2 PROTEIN; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; FEMALE; HETEROZYGOTE; HUMANS; JEWS; MIDDLE AGED; MUTAGENESIS, INSERTIONAL; MUTATION; NEOPLASM PROTEINS; PHEOCHROMOCYTOMA; SEQUENCE DELETION; TRANSCRIPTION FACTORS;

EID: 0035931704     PISSN: 01487299     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-8628(20010122)98:3<277::AID-AJMG1082>3.0.CO;2-Q     Document Type: Letter

References (15)

1. The founder mutations 185delAG and 5382insC in BRCA1 and 6174delT in BRCA2 appear in 60% of ovarian cancer and 30% of early-onset breast cancer patients among Ashkenazi women
2. The 185delAG BRCA1 mutation originated before the dispersion of Jews in the Diaspora and is not limited to Ashkenazim
3. Genetic linkage analysis in familial breast and ovarian cancer
4. Risks of cancer in BRCA1-mutation carriers
5. Sequence analysis of BRCA1 and BRCA2: Correlation of mutations with family history and ovarian cancer risk
6. The prevalence of common BRCA1 and BRCA2 Mutations among Ashkenazi Jews
7. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
8. High frequency of the 185delAG mutation in ovarian cancer in Israel
9. Direct detection of mutations in the breast and ovarian cancer susceptibility gene BRCA1 by PCR-mediated site-directed mutagenesis
10. Population genetics of BRCA1 and BRCA2
11. The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds
12. Denaturing high-performance liquid chromatography detects reliably BRCA1 and BRCA2 mutations