Regulation of steroidogenesis in transgenic mice and zebrafish

Molecular and Cellular Endocrinology

Volumn 171, Issue 1-2, 2001, Pages 9-14

  Hu, Meng Chun ^a   Chiang, Evelyn Feng Lin ^a   Tong, Sok Keng ^a   Lai, Wayne ^a   Hsu, Nai Chi ^a   Wang, Leo Chi Kwang ^a   Chung, Bon chu ^a  

^a INSTITUTE OF MOLECULAR BIOLOGY   (Taiwan)

Author keywords

Embryogenesis; P450scc; Side chain cleavage enzyme; Steroidogenesis; Y1 cells

Indexed keywords

CYCLIC AMP; CYTOCHROME P450 ISOENZYME; HYPOPHYSIS HORMONE; STEROID HORMONE; STEROIDOGENIC FACTOR 1;

ADRENAL GLAND; ANIMAL MODEL; ARTICLE; BINDING SITE; DEVELOPMENT; EMBRYO DEVELOPMENT; GENE CONTROL; GENE EXPRESSION; GONAD; HORMONAL REGULATION; HORMONE SYNTHESIS; HUMAN; MEDIATOR; MODEL; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY MECHANISM; STEROIDOGENESIS; TRANSGENIC MOUSE; ZEBRA FISH;

ADRENAL GLANDS; ANIMALS; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; CYCLIC AMP; GENE EXPRESSION REGULATION; GONADS; MICE; MICE, TRANSGENIC; MODELS, ANIMAL; PITUITARY HORMONES; PROMOTER REGIONS (GENETICS); STEROIDS; ZEBRAFISH;

EID: 0035931308     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(00)00385-3     Document Type: Article

References (36)

1. Regulation of cytochrome P450scc synthesis and activity in the ovine corpus luteum
2. Characterization of the upstream of the human CYP11A1 gene for cell type-specific expression
3. Transcriptional regulation of the CYP11A1 and ferredoxin genes
4. Steroidogenic factor-1 binding and transcriptional activity of the cholesterol side-chain cleavage promoter in rat granulosa cells
5. The gonadal steroids
6. Cell-type specificity of human CYP11A1 TATA box
7. Differential regulation of the CYP11A1 (P450scc) and ferredoxin genes in adrenal and placental cells
8. Actions of two different cAMP-responsive sequences and an adrenal enhancer of human CYP11A1 (P450scc) gene in adrenal Y1 and placental JEG-3 cells
9. Tissue-specific, hormonal, and developmental regulation of SCC-LacZ expression in transgenic mice leads to adrenocortical zone characterization
10. Regulated expression of cytochrome P-450scc (cholesterol-side-chain cleavage enzyme) in cultured cell lines detected by antibody against bacterially expressed human protein
11. Cloning of factors related to HIV-inducible LBP proteins that regulate steroidogenic factor-1-independent human placental transcription of the cholesterol side-chain cleavage enzyme, P450scc
12. Characterization of placental transcriptional activation of the human gene for P450scc
13. Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylase
14. Transcriptional regulation of steroid hydroxylase genes by corticotropin
15. Cholesterol side-chain cleavage cytochrome P450 gene expression in the primitive gut of the mouse embryo does not require steroidogenic factor 1
16. Induction of synthesis of mitochondrial steroidogenic enzymes of bovine adrenocortical cells by analogs cyclic AMP
17. Regulation of CYP11A gene expression in bovine ovarian granulosa cells in primary culture by cAMP and phorbol esters is conferred by a common cis-acting element
18. In vivo effects of adrenocorticotropin on hamster adrenal steroidogenic enzymes
19. Steroidogenic adrenocortical cell lines produced by genetically targeted tumorigenesis in transgenic mice
20. Molecular biology of steroid hormone synthesis
21. The molecular genetics of 21-hydroxylase deficiency
22. Identification of positive and negative placenta-specific basal elements and a cyclic adenosine 3′,5′-monophosphate response element in the human gene for P450scc
23. Variegated expression of a mouse steroid 21-hydroxylase/β-galactosidase transgene suggests centripetal migration of adrenocortical cells.
24. Activation of CYP11A and CYP11B gene promoters by the steroidogenic cell-specific transcription factor, Ad4BP
25. The cloning of a family of genes that encode the melanocortin receptors
26. Rat cholesterol side-chain cleavage cytochrome P-450 (P-450scc) gene structure and regulation by cAMP in vitro
27. Regulation of expression of steroidogenic enzymes in Leydig cells
28. Epidermal growth factor and c-Jun act via a common DNA regulatory element to stimulate transcription of the ovine P-450 cholesterol side chain cleavage (CYP11A1) promoter
29. Analysis of the promoter region of the gene encoding mouse cholesterol side-chain cleavage enzyme
30. Adrenocortical Y1 cells
31. Regulation of the synthesis of steroidogenic enzymes in adrenal cortical cells by ACTH
32. Regulation of the acute production of steroids in steroidogenic cells
33. Inherited congenital adrenal hyperplasia in the rabbit is caused by a deletion in the gene encoding cytochrome P450 cholesterol side-chain cleavage enzyme
34. Transcriptional regulation of P450scc gene expression in neural and steroidogenic cells: implications for regulation of neurosteroidogenesis