From gene to disease: From DNA mismatch repair genes to hereditary non-polyposis colorectal carcinoma;Van gen naar ziekte; van DNA-'mismatch'-herstelgenen naar hereditair non-polyposis-colonrectumcarcinoom

Nederlands Tijdschrift voor Geneeskunde

Volumn 145, Issue 16, 2001, Pages 780-782

  Wijnen, J T ^a   Morreau, H ^a   Vasen, H F A ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AUTOSOMAL DOMINANT DISORDER; BASE MISPAIRING; COLORECTAL CANCER; DISEASE ASSOCIATION; DNA REPAIR; ENDOMETRIUM CANCER; FAMILIAL CANCER; GENE MUTATION; GENETIC PREDISPOSITION; MICROSATELLITE INSTABILITY; ONSET AGE; SMALL INTESTINE CANCER; STOMACH CANCER;

AGE OF ONSET; BASE PAIR MISMATCH; COLONIC NEOPLASMS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; COMORBIDITY; DNA REPAIR; DNA, NEOPLASM; ENDOMETRIAL NEOPLASMS; FEMALE; GERM-LINE MUTATION; HUMANS; MALE; MICROSATELLITE REPEATS; NETHERLANDS; OVARIAN NEOPLASMS; RECTAL NEOPLASMS; STOMACH NEOPLASMS; UROLOGIC NEOPLASMS;

EID: 0035926127     PISSN: 00282162     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: An updated review
2. New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC
3. Biochemistry and genetics of eukaryotic mismatch repair
4. Mismatch repair in replication fidelity, genetic recombination, and cancer biology
5. Mutations predisposing to hereditary nonpolyposis colorectal cancer: Database and results of a collaborative study
6. Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N′-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLHI mutation
7. Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer
8. A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
9. Clinical findings with implications for genetic testing in families with clustering of colorectal cancer
10. Familial endometrial cancer in female carriers of MSH6 germline mutations