Sensitive liquid chromatography-tandem mass spectrometry method for the determination of loratadine and its major active metabolite descarboethoxyloratadine in human plasma

Journal of Chromatography A

Volumn 914, Issue 1-2, 2001, Pages 37-43

  Sutherland, F C W ^a   De Jager, A D ^a   Badenhorst, D ^a   Scanes, T ^a   Hundt, H K L ^a   Swart, K J ^a   Hundt, A F ^a  

^a UNIVERSITY OF THE FREE STATE   (South Africa)

Author keywords

Descarboethoxyloratadine; Loratadine; Validation

Indexed keywords

ENZYMES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION; MASS SPECTROMETRY; TOLUENE;

DESCARBOETHOXYLORATADINE (DCL);

METABOLITES;

DESLORATADINE; FLUOXETINE; FLUSPIRILENE; LORATADINE;

ANALYTIC METHOD; ARTICLE; BIOLOGICAL MONITORING; CONTROLLED STUDY; DEVICE; DRUG DETERMINATION; DRUG STRUCTURE; ELECTROCHEMICAL DETECTION; EVAPORATION; HUMAN; LIQUID CHROMATOGRAPHY; METABOLITE; PLASMA; PRIORITY JOURNAL; QUANTITATIVE ASSAY; REACTION TIME; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HISTAMINE H1 ANTAGONISTS; HUMANS; LORATADINE; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 0035917990     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9673(01)00646-X     Document Type: Article

References (9)