SQ22536 and W-7 inhibit forskolin-induced cAMP elevation but not relaxation in newborn ovine pulmonary veins

European Journal of Pharmacology

Volumn 418, Issue 1-2, 2001, Pages 111-116

  Gao, Yuansheng ^a   Raj, J Usha ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HARBOR UCLA MEDICAL CENTER   (United States)

Author keywords

Adenylyl cyclase; cAMP; Pulmonary vein; Smooth muscle, Vascular

Indexed keywords

9 (TETRAHYDRO 2 FURYL)ADENINE; CYCLIC AMP; FORSKOLIN; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE;

ANIMAL TISSUE; ARTICLE; BLOOD VESSEL TONE; ENZYME ACTIVITY; LAMB; NONHUMAN; PRIORITY JOURNAL; PULMONARY VEIN; SMOOTH MUSCLE RELAXATION;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ADENINE; ADENYLATE CYCLASE; ANIMALS; ANIMALS, NEWBORN; CELL MEMBRANE; CYCLIC AMP; CYCLIC GMP; ENDOTHELIN-1; ENZYME INDUCTION; FEMALE; FORSKOLIN; MALE; MUSCLE, SMOOTH, VASCULAR; PULMONARY VEINS; SHEEP; SULFONAMIDES; THIONUCLEOTIDES; TIME FACTORS; VASODILATION;

EID: 0035917593     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)00929-3     Document Type: Article

References (29)

1. Antagonism of calmodulin-stimulated adenylate cyclase by trifluoperazine, calmidazolium and W-7 in rat cerebellar membranes
2. A rapid method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding
3. Inhibition of cyclic GMP-dependent protein kinase-mediated effects by (Rp)-8-bromo-PET- cyclic GMPS
4. Forskolin, adenylate cyclase, and cell physiology: An overview
5. Involvement of cGMP-dependent protein kinase in the relaxation of ovine pulmonary arteries to cGMP and cAMP
6. +-induced responses in chromaffin cells
7. Endothelium-derived nitric oxide plays a larger role in pulmonary veins than in arteries of newborn lambs
8. 2 cause greater relaxations in pulmonary veins than in arteries of newborn lambs
9. Developmental change in isoproterenol-mediated relaxation of pulmonary veins of fetal and newborn lambs
10. Novel (Rp)-cAMPS analogs as tools for inhibition of cAMP-kinase in cell culture. Basal cAMP-kinase activity modulates interleukin-1 beta action
11. Forskolin reduces a transient potassium current in lobster neurons by a cAMP-independent mechanism
12. Inhibition of adenylate cyclase by adenosine analogues in preparations of broken and intact human platelets. Evidence for the unidirectional control of platelet function by cyclic AMP
13. + channels is independent of adenylate cyclase activation
14. Direct evidence for cross-activation of cGMP-dependent protein kinase by cAMP in pig coronary arteries
15. Analogs of cyclic AMP and cyclic GMP: General methods of synthesis and the relationship of structure to enzymic activity
16. 2+-sensitive adenylyl cyclases, key integrators of cellular signalling
17. Cyclic AMP and mechanisms of vasodilation
18. Cyclic AMP-independent inhibition of voltage-sensitive calcium channels by forskolin in PC12 cells
19. Forskolin: Its biological and chemical properties
20. Forskolin: Unique diterpene activator of adenylate cyclase in membranes and in intact cells
21. Complexity and diversity of mammalian adenylyl cyclases
22. Effects of the adenylyl cyclase inhibitor SQ22536 on iloprost-induced vasorelaxation and cyclic AMP elevation in isolated guinea-pig aorta
23. Inhibitors of prostaglandin, prostacyclin, and thromboxane synthesis
24. Comparison of the effects of forskolin and isoproterenol on cyclic AMP levels and tension in bovine coronary artery
25. 1, isoproterenol and forskolin on cyclic AMP levels and tension in rabbit aortic rings
26. Forskolin interaction with voltage-dependent K channels in Helix is not mediated by cyclic nucleotides
27. 2+ channel blocker-like action in rat cerebellar granule cells
28. - channels in cAMP-induced pulmonary vasodilation
29. Agonist-related differences in the relationship between cAMP content and protein kinase activity in canine trachealis