Sequential detection of alphafetoprotein-bearing cells in blood stem cell fraction of germ cell tumour patients

British Journal of Cancer

Volumn 85, Issue 8, 2001, Pages 1119-1123

  Kasahara, T ^a,b   Hara, N ^a   Bilim, V ^a   Tomita, Y ^a   Saito, K ^b   Obara, K ^b   Takahashi, K ^b  

^a NIIGATA UNIVERSITY   (Japan)

^b NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

Author keywords

Alphafetoprotein; Germ cell tumour; Peripheral blood stem cells; Reverse transcription polymerase chain reaction

Indexed keywords

ALPHA FETOPROTEIN; CARBOPLATIN; COMPLEMENTARY DNA; ETOPOSIDE; IFOSFAMIDE; STEM CELL FACTOR;

ADULT; ADVANCED CANCER; ARTICLE; CANCER RECURRENCE; CANCER STAGING; CONTROLLED STUDY; DRUG MEGADOSE; GERM CELL TUMOR; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; PRIORITY JOURNAL; PROTEIN DETERMINATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEMINOMA; STEM CELL TRANSPLANTATION; TREATMENT OUTCOME;

ADULT; ALPHA-FETOPROTEINS; GERMINOMA; HEMATOPOIETIC STEM CELLS; HUMANS; NEOPLASM, RESIDUAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SENSITIVITY AND SPECIFICITY;

EID: 0035914256     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.2001.2050     Document Type: Article

References (29)

1. Bone marrow transplantation
2. Long-term survival of patients with recurrent or refractory germ cell tumors after high dose chemotherapy
3. Absence of frameshift mutations in the bax gene in renal cell cancer (RCC) and transitional cell cancer (TCC)
4. Gene-marking to trace origin of relapse after autologous bone-marrow transplantation
5. Tandem high dose chemotherapy with autologous bone marrow transplantation for initial relapse of testicular germ cell cancer
6. Occult tumor contamination of hematopoietic stem-cell products does not affect clinical outcome of autologous transplantation in patients with metastatic breast cancer
7. Molecular detection of tumor contamination in peripheral blood stem cell harvests
8. Phase I study of high dose ifosfamide, carboplatin and etoposide with autologous hematopoietic stem cell support
9. Detection of germ cell tumor cells in apheresis products using polymerase chain reaction
10. Maximum tolerated doses of ifosfamide, carboplatin, and etoposide given over 6 days followed by autologous stem-cell rescue: Toxicity profile
11. Clinical significance of bone marrow metastases as detected using the polymerase chain reaction in patients with breast cancer undergoing high-dose chemotherapy and autologous bone marrow transplantation
12. Molecular detection of micrometastases and circulating tumor cells in solid tumors
13. Immunologic purging of marrow assessed by PCR before autologous bone marrow transplantation for B-cell lymphoma
14. Detection of alphafetoprotein-expressing cells in the blood of patients with hepatoma and hepatitis
15. Phase I trial of interferon gamma to potentiate cyclosporine-induced graft-versus host disease in women undergoing autologous bone marrow transplantation for breast cancer
16. Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen
17. Sensitive detection of circulating hepatocellular carcinoma cells in peripheral venous blood
18. Monitoring of tumor cell purging after highly efficient immunomagnetic selection of CD34 cells from leukapheresis products in breast cancer patients: Comparison of immunocytochemical tumor cell staining and reverse transcriptase-polymerase chain reaction
19. Sensitive detection of rare circulating neuroblastoma cells by the reverse transcriptase-polymerase chain reaction
20. Primary structures of human alpha-fetoprotein and its mRNA
21. Contamination of peripheral blood stem cell harvests by circulating neuroblastoma cells
22. High-dose carboplatin and etoposide with autologous bone marrow transplantation in refractory germ cell cancer: An Eastern Cooperative Oncology Group protocol
23. Similar breast cancer cell contamination of single-day peripheral-blood progenitor-cell collections obtained after priming with hematopoietic growth factor alone or after cyclophosphamide followed by growth factor
24. Direct demonstration that autologous bone marrow transplantation for solid tumors can return a multiplicity of tumorigenic cells
25. Tumor cell contamination of peripheral blood stem cell transplants and bone marrow in high-risk breast cancer patients
26. Purging of mammary carcinoma cells during ex vivo culture of CD34+ hematopoietic progenitor cells with recombinant immunotoxins
27. Evaluation of breast tumour cell contamination in the bone marrow and leukapheresis collections by RT-PCR for cytokeratin-19 mRNA
28. Ex vivo expansion of CD34+ peripheral blood progenitor cells: Implications for the expansion of contaminating epithelial tumor cells
29. The significance of tumor contamination in the bone marrow from high-risk primary breast cancer patients treated with high-dose chemotherapy and hematopoietic support