A convergent approach to the mitomycin ring system

Organic Letters

Volumn 3, Issue 8, 2001, Pages 1141-1144

  Coleman, Robert S ^a   Chen, Wei ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; MITOMYCIN; PYRROLE DERIVATIVE; PYRROLINE;

ARTICLE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS;

ALKYLATING AGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MITOMYCIN; MODELS, CHEMICAL; MODELS, MOLECULAR; PYRROLES;

EID: 0035912362     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol0156244     Document Type: Article

References (36)

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29. Not surprisingly, the dihydroindole ring system of 14 was sensitive to air oxidation, and the modest isolated yield for the cyclization of 13 to 14 is in part due to this sensitivity.
30. 2 + H, 233.1290).
31. 3, 125 MHz) δ 156.65, 154.91, 129.60, 128.77, 125.25, 119.40, 111.35, 68.82, 67.82, 51.98, 46.55, 30.83, 25.68.
32. The stereochemical series with a cis relationship between C9-H/ C9a-H is denoted trans by Chemical Abstracts Service. Before 1983, the 9R*,9aR* series with a cis-relationship between C9-H/C9a-H was denoted as cis. Because of this confusing reversal of notation, we have avoided using cis and trans altogether in naming our compounds. Thus, the 9R*,-9aR* stereoisomer has the C9-H and C9a-H on the same face of the molecule, wereas the 9R*,9aS* stereoisomer has them on opposite sides.
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