Schwann cells responding to primary demyelination in vivo express p75(NTR) and c-erbB receptors: A light and electron immunohistochemical study

Journal of Neurocytology

Volumn 26, Issue 10, 1997, Pages 679-690

  Hall, S M ^a   Li, H ^a   Kent, A P ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LYSOPHOSPHATIDYLCHOLINE; NEU DIFFERENTIATION FACTOR; NEUROTROPHIN RECEPTOR; RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEMYELINATION; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; REMYELINIZATION; SCHWANN CELL; SCIATIC NERVE;

ANIMALS; CATTLE; DEMYELINATING DISEASES; IMMUNOHISTOCHEMISTRY; LYSOPHOSPHATIDYLCHOLINES; MICE; MICROSCOPY, IMMUNOELECTRON; PROLIFERATING CELL NUCLEAR ANTIGEN; RABBITS; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; RECEPTOR, NERVE GROWTH FACTOR; RECEPTORS, NERVE GROWTH FACTOR; SCHWANN CELLS;

EID: 0030823749     PISSN: 03004864     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018502012347     Document Type: Article

References (87)

1. ANTON, E. S., WESKAMP, G. REICHARDT, L. F. & MATTHEW, W. D. (1994) Nerve growth factor and its low affinity receptor promote Schwann cell migration. Proceedings of the National Academy of Sciences, USA 91, 2795-9.
2. BANERJEE, A., ROACH, M. C., TRCKA, P. & LUDUENA, R. F. (1992) Increased microtubule assembly in bovine brain tubulin lacking the type III isotype of beta-tubulin. Journal of Biological Chemistry 265, 1794-9.
3. BANNERJEE, S. A. & PATTERSON, P. H. (1995) Schwann cell CD9 expression is regulated by axons. Molecular and Cellular Neuroscience 6, 462-73.
4. BENEDETTI, M., LEVI, A. & CHAO, M. V. (1993) Differential expression of nerve growth factor receptors leads to altered binding affinity and neurotrophin responsive-ness. Proceedings of the National Academy of Sciences, USA 90, 7859-63.
5. BOLIN, L. M. & SHOOTER, E. M. (1993) Neurons regulate Schwann cell genes by diffusible molecules. Journal of Cell Biology 123, 237-43.
6. BRAVO, R. & MACDONALD-BRAVO, H. (1987) Existence of two populations of cyclin/proliferating cell nuclear antigen during the cell cycle: association with DNA replication sites. Journal of Cell Biology 105, 1549-54.
7. BYERS, M. R., KVINNSLAND, I. & BOTHWELL, M. (1992) Analysis of low affinity nerve growth factor receptor during pulpal healing and regeneration of myelinated and unmyelinated axons in replanted teeth. Journal of Comparative Neurology 326, 470-84.
8. CARRAWAY III, K. L. & CANTLEY, L. C. (1994) A neu acquaintance for erbB3 and erbB4: a role for receptor heterodimerization in growth signalling. Cell 78, 5-8.
9. CARRAWAY III, K. L. & BURDEN, S. J. (1995) Neuregulins and their receptors. Current Opinion in Neurobiology 5, 606-12.
10. CARROLL, S. L., MILLER, M. L., FROHNERT, P. W., KIM, S. S. & CORBETT, J. A. (1997) Expression of neuregulins and their putative receptors, erbB2 and erbB3, is induced during Wallerian degeneration. Journal of Neuroscience 17, 1642-59.
11. CASSACIA-BONNEFIL, P., CARTER, B. D., DOBROWSKY, R. T. & CHAO, M. V. (1996) Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75. Nature 383, 716-19.
12. CLARK, M. B., ZEHEB, R., WHITE, T. K., & BUNGE, R. P. (1991) Schwann cell plasminogen activator is regulated by neurons. Glia 4, 514-28.
13. COHEN, J. A., YACHNIS, A. T., ARAI, M., DAVIS, J. G. & SCHERER, S. S. (1992) Expression of the neu protooncogene by Schwann cells during peripheral nerve development and Wallerian degeneration. Journal of Neuroscience Research 31, 622-34.
14. 2-peptide induced experimental allergic neuritis. Neuroscience Letters 199, 135-8.
15. CURTIS, R., STEWART, H. J. S., HALL, S. M., WILKIN,G. P., MIRSKY, R. & JESSEN, K. R. (1992) GAP-43 is expressed by nonmyelin-forming Schwann cells of the peripheral nervous system. Journal of Cell Biology 116, 1455-64.
16. CURTIS, R., ADRYAN, K. M., STARK, J. L., PARK, J. S., COMPTON, D. L., WESKAMP, G., HUBER, L, J., CHAO, M. V., JAENISCH, R., et al. (1995) Differential role of the low affinity neurotrophin receptor (p75) in retrograde axonal transport of the neurotrophins. Neuron 14, 1201-11.
17. DOBROWSKY, R. T., WERNER, M. H., CASTELLINO, A. M., CHAO, M. V. & HANNUN, Y. A. (1994) Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor. Science 265, 15-9.
18. DONG, Z., BRENNAN, A., LIU, N., YARDEN, Y., LEFKOWITZ, G., MIRSKY, R. & JESSEN, K. R. (1995) Neu differentiation factor is a neuron-glia signal and regulates survival, proliferation, and maturation of rat Schwann cell precursors. Neuron 15, 585-96.
19. DOYU, M., SOBUE, G., KEN, E., KIMATA, K., SHINOMURA, T., YAMADA, Y., MITSUMA, T. & TAKAHASHI, A. (1993) Laminin A, B1, and B2 chain gene expression in transected and regenerating nerves: regulation by axonal signals. Journal of Neurochemistry 60, 543-51.
20. EKSTROM, P. A. (1995) Neurones and glial cells of the mouse sciatic nerve undergo apoptosis after injury in vivo and in vitro. Neuroreport 6, 1029-32.
21. FALLS, D. L., ROSEN, K. M., CORFAS, G., LANE, W. S. & FISCHBACH, G. D. (1993) ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family. Cell 72, 801-15.
22. FANN, X. & GELMAN, B. B. (1992) Schwann cell nerve growth factor receptor expression during initiation of remyelination. Journal of Neuroscience Research 31, 58-67.
23. FRADE, J. M., RODRIGUEZ-TEBAR, A. & BARDE, Y. A. (1996) Induction of cell death by endogenous nerve growth factor through its p75 receptor. Nature 383, 166-8.
24. GEISERT, E. E. Jr. & FRANKFURTER, A. (1989) The neuronal response to injury as visualised by immuno-staining of class III β-tubulin in the rat. Neuroscience Letters 102, 137-41.
25. GREGSON, N. A. & HALL, S. M. (1973) A quantitative analysis of the effects of the intraneural injection of lysophosphatidyl choline. Journal of Cell Science 13, 257-77.
26. GRIFFIN, J. W., STOCKS, E. A., FAHNESTOCK, M., VAN PRAAGH, A. & TRAPP, B. D. (1990) Schwann cell proliferation following lysolecithin-induced demyelination. Journal of Neurocytology 19, 367-84.
27. GRINSPAN, J. B., MARCHIONNI, M. A., REEVES, M., COULALOGLOU, M. & SCHERER, S. S. (1996) Axonal interactions regulate Schwann cell apoptosis in developing peripheral nerve: neuregulin receptors and the role of neuregulins. Journal of Neuroscience 16, 6107-118.
28. HALL, S. M. (1988) Neurotoxic effects of lysolecithin, mouse, rat. In Monographs on Pathology of Laboratory Animals. Nervous System (edited by JONES, T. C., MOHR, U. & HUNT, R. D.) pp. 63-73. Berlin: Springer-Verlag.
29. HALL, S. M. & GREGSON, N. A. (1971) The in vivo and ultrastructural effects of injection of lysophosphatidyl choline into myelinated peripheral nerve fibres of the adult mouse. Journal of Cell Science 9, 769-89.
30. HEMPSTEAD, B. L., MARTIN-ZANCA, D., KAPLAN, D. R., PARADA, L. F. & CHAD, M. V. (1991) Coexpression of the trk proto-oncogene and the low-affinity NGF receptor required for high-affinity NGF binding. Nature 350, 678-83.
31. HEUMANN, R., KORSCHING, S., BANDTLOW, C. & THOENEN, H. (1986) Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection. Journal of Cell Biology 104, 1623-31.
32. HEUMANN, R., LINDHOLM, D., BANDTLOW, C., MEYER, M., RADEKE, M. E., MISKO, T. P., SHOOTER, E. M. & THOENEN, H. (1987) Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerves during development, degeneration and regeneration. Proceedings of the National Academy of Sciences, USA 84, 8735-9.
33. erbB2. Science 256, 1205-10.
34. JESSEN, K. R., BRENNAN, A., MORGAN, L., MIRSKY, R., KENT, A., HASHIMOTO, Y. & GAVRILOVIC, J. (1994) The Schwann cell precursor and its fate: a study of cell death and differentiation during gliogenesis in rat embryonic nerves. Neuron 12, 509-27.
35. JESSEN, K. R., MIRSKY, R. & MORGAN, L. (1987) Axonal signals regulate the differentiation of non- myelin-forming Schwann cells: an immunohistochemical study of galactocerebroside in transected and regenerating nerves. Journal of Neuroscience 7, 3362-9.
36. JESSEN, K. R., MORGAN, L., STEWART, H. J. S. & MIRSKY, R. (1990) Three markers of adult nonmyelin-forming Schwann cells, (Ran-1), A5E3 and GFAP: development and regulation by neuron- Schwann cell interactions. Development 109, 91-103.
37. JING, S., TAPLEY, P. & BARBACID, M. (1992) Nerve growth factor mediates signal transduction through trk homodimer receptors. Neuron 9, 67-79.
38. KORSCHING, S. (1993) The neurotrophic factor concept: a re-examination. Journal of Neuroscience 13, 2739-48.
39. KUECHERER-EHRET, A., GRAEBER, M. B., EDGAR, D., THOENEN, H. & KREUTZBERG, G. W. (1990) Immunoelectron microscopic localization of laminin in normal and regenerating mouse sciatic nerve. Journal of Neurocytology 19, 101-9.
40. LEFCORT, F., VENSTROM, K., MCDONALD, J. A. & REICHARDT, L. F. (1992) Regulation of expression of fibronectin and its receptor alpha 5 beta 1, during development and regeneration of peripheral nerve. Development 116, 767-82.
41. LEMKE, G. & CHAO, M. (1988) Axons regulate Schwann cell expression of the major myelin and NGF receptor genes. Development 102, 499-504.
42. LEVI, A. D. O., BUNGE, R. P., LOFGREN, J. A., MEIMA, L., HEFTI, F., NIKOLICS, K. & SLIWKOWSKI, M. X. (1995) The influence of heregulins on human Schwann cell proliferation. Journal of Neuroscience 15, 1329-40.
43. LEVI-MONTALCINI, R., SKAPER, S. D., TOSO, R. D., PETRELLI, L. & LEON, A. (1996) Nerve growth factor: from neurotrophin to neurokin. Trends in Neuroscience 19, 514-20.
44. LI, H., NEWCOMBE, J. & CUZNER, M. L. (1993) Characterization and distribution of phagocytic macrophages in multiple sclerosis plaques. Neuropathology and Applied Neurobiology 19, 214-23.
45. LI, H., TERENGHI, G. & HALL, S. M. (1997) The effects of delayed re-innervation on the expression of c-erbB receptors by chronically denervated rat Schwann cells in vivo. Glia 20, 333-47.
46. MAHANTHAPPA, N. K., ANTON, E. S. & MATTHEW, W. D. (1996) Glial growth factor 2, a soluble neuregulin, directly increases Schwann cell motility and indirectly promotes neurite outgrowth. Journal of Neuroscience 16, 4673-83.
47. MARCHIONNI, M. A., GOODEARL, A. D. J., CHEN, M. S., BERMINGHAM-MCDONOGH, O., KIRK, C., HENDRICKS, M., DANEHY, F., MISUMI, D., SUDHALTER, J., KOBAYASHI, K., WROBLEWSKI, D., LYNCH, C., BALDASSARE, M., HILES, I., DAVIS, J. B., HSUAN, J. J., TOTTY, N. F., OTSU, M., MCBURNEY, R. N., WATERFIELD, M. D., STROOBANT, P. & GWYNNE, D. (1993) Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system. Nature 362, 312-18.
48. MARTINI, R. & SCHACHNER, M. (1988) Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and myelin-associated glycoprotein) in regenerating adult mouse sciatic nerve. Journal of Cell Biology 106, 1735-46.
49. MARTINI, R., SCHACHNER, M. & FAISSNER, A. (1990) Enhanced expression of the extracellular matrix molecule J1/tenascin in the regenerating adult mouse sciatic nerve. Journal of Neurocytology 19, 601-16.
50. MASON, P., NEUBERGER, T., ATTEMA, B. & DE VRIES, G. (1993) Regulation of neu expression in Schwann celldorsal root ganglion co-cultures. Society of Neuroscience Abstracts 19, 540.8.
51. MATSUOKA, I., MEYER, M. & THOENEN, H. (1991) Cell- type-specific regulation of nerve growth factor synthesis in non-neuronal cells: comparison with other cell types. Journal of Neuroscience 11, 3165-77.
52. MCCORMICK, D. & HALL, P. A. (1992) The complexities of proliferating cell nuclear antigen. Histopathology 21, 591-4.
53. MEYER, D. & BIRCHMEIER, C. (1994) Distinct isoforms of neuregulin are expressed in mesenchymal and neuronal cells during mouse development. Proceedings of the National Academy of Sciences, USA 91, 1064-8.
54. MEYER, D. & BIRCHMEIER, C. (1995) Multiple essential functions of neuregulin in development. Nature 378, 386-90.
55. MEYER, M., MATSUOKA, I., WETMORE, C. & THOENEN, H. (1992) Enhanced synthesis of brain- derived neurotrophic factor in the lesioned peripheral nerve: different mechanisms are responsible for the regulation of BDNF and NGF mRNA. Journal of Cell Biology 119, 45-54.
56. MITCHELL, L. S., GRIFFITHS, I. R., MORRISON, S., BARRIE, J. A., KIRKHAM, A. & MCPHILMEY, K. (1990) Expression of myelin protein gene transcripts by Schwann cells of regenerating nerve. Journal of Neuroscience 27, 125-35.
57. MORRIS, R. J., BARBER, P. C., BEECH, J. & RAISMAN, G. (1983) The distribution of Thy-1 antigen in the P.N.S. of the adult rat. Journal of Neurocytology 12, 1017-39.
58. erbB2. Proceedings of the National Academy of Sciences, USA 92, 1431-5.
59. erbB4, a fourth member of the epidermal growth factor receptor family. Proceedings of the National Academy of Sciences, USA 90, 1746-50.
60. erbB4. Nature 366, 473-75.
61. RAABE, T. D., CLIVE, D. R., NEUBERGER, T. J., WEN, D. & DEVRIES, G. H. (1996) Cultured neonatal Schwann cells contain and secrete neuregulins. Journal of Neuroscience Research 46, 263-70.
62. RABIZADEH, S., OH, J., ZHONG, L. T., YANG, J., BITLER, C. M., BUTCHER, L. L. & BREDESEN, D. E. (1993) Induction of apoptosis by the low-affinity NGF receptor. Science 261, 345-8.
63. RATNER, N., HONG, D., LIEBERMAN, M. A., BUNGE, R. P. & GLASER, L. (1988) The neuronal cell-surface molecule mitogenic for Schwann cells is a heparin- binding protein. Proceedings of the National Academy of Sciences, USA 85, 6992-6.
64. REDD, P. E. & BYERS, M. R. (1994) Regeneration of junctional epithelium and its innervation in adult rats: a study using immunocytochemistry for p75 nerve growth factor receptor and calcitonin gene-related peptide. Journal of Periodontal Research 29, 214-24.
65. ROBERSON, M. D., TOEWS, A. D., BOULDIN, T. W., WEAVER, J., GOINES, N. D. & MORELL, P. (1995) NGFR-mRNA expression in sciatic nerve: a sensitive indicator of early stages of axonopathy. Molecular Brain Research 28, 231-8.
66. SALZER, J. L., BUNGE, R. P. & GLASER, L. (1980) Studies of Schwann cell proliferation. III Evidence for the surface localization of the neurite mitogen. Journal of Cell Biology 84, 767-78.
67. SCHECHTER, A. L., HUNG, M-C., VAIDYANATHAN, L. & WEINBERG, R. A. (1985) The neu gene: An erbB-homologous gene distinct from and unlinked to the gene encoding the EGF receptor. Science 229, 976-78.
68. SEILHEIMER, B. & SCHACHNER, M. (1987) Regulation of neural cell adhesion molecule expression on cultured mouse Schwann cells by nerve growth factor. EMBO Journal 6, 1611-16.
69. SHAH, N. M., MARCHIONNI, M. A., ISAACS, I., STROOBANT, P. & ANDERSON, D. J. (1994) Glial growth factor restricts mammalian neural crest stem cells to a glial fate. Cell 77, 349-60.
70. SMITH, K. J., BOSTOCK, H. & HALL, S. M. (1982) Saltatory conduction precedes remyelination in axons demyelinated with lysophosphatidyl choline. Journal of the Neurological Sciences 54, 13-31.
71. SMITH, K. J., HALL, S. M. & SCHAUF, C. L. (1985) Vesicular demyelination induced by raised intracellular calcium. Journal of the Neurological Sciences 71, 19-37.
72. SMITH, K. J. & HALL, S. M. (1988) Peripheral demyelination and remyelination initiated by the calcium-selective ionophore ionomycin: in vivo observations. Journal of the Neurological Sciences 83, 37-53.
73. STEEDMAN, H. F. (1957) Polyester wax. A new ribboning embedding medium for histology. Nature 179, 1345-6.
74. STOLL, G., LI, C. Y., TRAPP, B. D. & GRIFFIN, J. W. (1993) Expression of NGF receptors during immune-mediated and lysolecithin-induced demyelination of the peripheral nervous system. Journal of Neurocytology 22, 1022-9.
75. SUDHALTER, J., WHITEHOUSE, L., RUSCHE, J. R., MARCHIONNI, M. & MAHANTHAPPA, N. K. (1996) Schwann cell heparan sulfate proteoglycans play a critical role in glial growth factor/neuregulin signalling. Glia 17, 28-39.
76. TANIUCHI, M., CLARK, H. B. & JOHNSON, E. M. (1986) Induction of nerve growth factor receptor in Schwann cells after axotomy. Proceedings of the National Academy of Sciences, USA 83, 4094-8.
77. THOMSON, C. E., GRIFFITHS, I. R., MCULLOUGH, M. C., KYRIAKIDES, E., BARRIE, J. A. & MONTAGUE, P. (1993) In vitro studies of axonally-regulated Schwann cell genes during Wallerian degeneration. Journal of Neurocytology 22, 590-602.
78. TOEWS, A. D., GRIFFITHS, I. R., KYRIAKIDES, E., GOODRUM, J. F., ECKERMANN, C. E., MORELL, P. & THOMSON, C. E. (1992) Primary demyelination induced by exposure to tellurium alters Schwann cell gene expression: a model for intracellular targeting of NGF receptor. Journal of Neuroscience 12, 3676-87.
79. TOMA, J. G., PAREEK, S., BARKER, P., MATHEW, T. C., MURPHY, R. A., ACHESON, A. & MILLER, F. D. (1992) Spatiotemporal increases in epidermal growth factor receptors following peripheral nerve injury. Journal of Neuroscience 12, 2504-15.
80. TRACHTENBERG, J. T. & THOMPSON, W. J. (1995) Schwann cell apoptosis at developing neuromuscular junctions is regulated by glial growth factor. Nature 379, 174-7.
81. TZAHAR, E., LEVKOWITZ, G., KARUNAGARAN, D., YI, L., PELES, E., LAVI, S., CHANG, D., LIU, N., YAYON, A., WEN, D. & YARDEN, Y. (1994) ErbB-3 and erbB-4 function as the respective low and high affinity receptors of all neu differentiation factor/ heregulin isoforms. Journal of Biological Chemistry 269, 25226-33.
82. WASEEM, N. H., & LANE, P. (1990) Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA). Structural conservation and the detection of a nucleolar form. Journal of Cell Science 69, 121-9.
83. WEN, D., PELES, E., CUPPLES, R., SUGGS, S. V., BACUS, S. S., LUO, Y., TRAIL, G., HU, S., SILBIGER, S. M., LEVY, R. B., KOSKI, R. A., LU, H. S. & YARDEN, Y. (1992) Neu differentiation factor: A transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit. Cell 69, 559-72.
84. WHITWORTH, I. H., BROWN, R. A., DORE, C., GREEN, C. J. & TERENGHI, G. (1995) Orientated mats of fibronectin as a conduit material for use in peripheral nerve repair. Journal of Hand Surgery (British Volume) 20, 429-36.
85. WILLISON, H. J., TRAPP, B. D., BACHER, J. D. & QUARLES, R. H. (1988) The expression of myelin- associated glycoprotein in regenerating cat sciatic nerve. Brain Research 444, 10-16.
86. WU, W., MATHEW, T. C. & MILLER, F. D. (1993) Evidence that the loss of homeostatic signals induces regeneration- associated alterations in neuronal gene expression. Developmental Biology 158, 456-66.
87. YAMAMOTO, M., KONDO, H. & ISEKI, S. (1992) Nerve growth factor receptor (NGFR)-like immunoreactivity in the perineurial cell in normal and sectioned peripheral nerves of rats. Anatomical Record 233, 301-8.