Suspension cultivation of Mycobacterium ulcerans for the production of mycolactones

FEMS Microbiology Letters

Volumn 205, Issue 2, 2001, Pages 385-389

  Cadapan, L D ^a   Arslanian, R L ^a   Carney, J R ^a   Zavala, S M ^a   Small, P L ^b   Licari, P ^a  

^a KOSAN BIOSCIENCES INC   (United States)

^b UNIVERSITY OF TENNESSEE   (United States)

Author keywords

Dispersed growth; Mycobacterium ulcerans; Mycolactone; Polyketide

Indexed keywords

POLYKETIDE;

ADAPTATION; ARTICLE; BACTERIAL GROWTH; BACTERIUM CULTURE; CONTROLLED STUDY; DRUG SYNTHESIS; FERMENTATION; MYCOBACTERIUM ULCERANS; NONHUMAN; PRIORITY JOURNAL; SKIN DISEASE; STRAIN DIFFERENCE;

BACTERIAL TOXINS; MOLECULAR STRUCTURE; MYCOBACTERIUM ULCERANS; TIME FACTORS;

MYCOBACTERIUM; MYCOBACTERIUM ULCERANS;

EID: 0035910150     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(01)00502-X     Document Type: Article

References (15)

1. Out of Africa: Observations on the histopathology of Mycobacterium ulcerans infection
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4. Immunosuppressive properties of the soluble toxin from Mycobacterium ulcerans
5. Partial purification and characterization of biological effects of a lipid toxin produced by Mycobacterium ulcerans
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7. Characterization of novel macrolide toxins, mycolactones A and B, from a human pathogen, Mycobacterium ulcerans
8. Stereochemistry of the core structure of the mycolactones
9. A Mycobacterium ulcerans toxin, mycolactone, causes apoptosis in guinea pig ulcers and tissue culture cells
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11. Effects of decontamination methods and culture conditions on viability of Mycobacterium ulcerans in the BACTEC system
12. Growth and cytotoxic activity by Mycobacterium ulcerans in protein-free media
13. The effect of organic acids, serum albumin, and wetting agents on log phase, dispersed growth and pH stabilization in mycobacterial cultures
14. Effect of oxygen on growth of Mycobacterium ulcerans in the BACTEC system
15. Microaerophilic conditions promote growth of Mycobacterium genavense