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Volumn 3, Issue 21, 2001, Pages 3377-3379

A convenient method for 3-pyrroline synthesis

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ANTIINFECTIVE AGENT; DRUG DERIVATIVE; LACTACYSTIN; LACTAM; PYRROLE DERIVATIVE; PYRROLINE;

EID: 0035909620     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol016603c     Document Type: Article
Times cited : (29)

References (32)
  • 5
    • 0002020843 scopus 로고    scopus 로고
    • For further examples of nitorgen heterocycle synthesis using alkylidene carbenes, see: (a) Yagi, T.; Aoyama, T.; Shiori, T. Synlett 1997, 1063.
    • (1997) Synlett , pp. 1063
    • Yagi, T.1    Aoyama, T.2    Shiori, T.3
  • 12
    • 0042755239 scopus 로고    scopus 로고
    • For full details see Supporting Information
    • For full details see Supporting Information.
  • 13
    • 0043256372 scopus 로고    scopus 로고
    • Taber et al. have shown that 50:50 mixtures of E/Z vinyl chlorides can be used to form cyclopentenes in high yields (90%). See ref 5c
    • Taber et al. have shown that 50:50 mixtures of E/Z vinyl chlorides can be used to form cyclopentenes in high yields (90%). See ref 5c.
  • 14
    • 0043256371 scopus 로고    scopus 로고
    • No evidence for 2-amino-cyclopropene (via 1,3-CH insertion) and/ or azetidene (via 1,4-NH insertion) formation was observed
    • No evidence for 2-amino-cyclopropene (via 1,3-CH insertion) and/ or azetidene (via 1,4-NH insertion) formation was observed.
  • 15
    • 0041753339 scopus 로고    scopus 로고
    • The observed ratio of the 3-pyrroline 9 and alkyne 5 products produced in the cyclization of 8 was independent of concentration and temperature over the range 0-25°C
    • The observed ratio of the 3-pyrroline 9 and alkyne 5 products produced in the cyclization of 8 was independent of concentration and temperature over the range 0-25°C.
  • 28
    • 0022342571 scopus 로고
    • We thank one referee for supplying useful additional references in this area
    • (l) Anderson, W. K.; Milowsky, A. S. J. Org. Chem. 1985, 50, 5423. We thank one referee for supplying useful additional references in this area.
    • (1985) J. Org. Chem. , vol.50 , pp. 5423
    • Anderson, W.K.1    Milowsky, A.S.2
  • 30
    • 0042755237 scopus 로고    scopus 로고
    • For full details see Supporting Information
    • For full details see Supporting Information.
  • 31
    • 0042755236 scopus 로고    scopus 로고
    • 1H NMR analysis of the crude reaction mixtures). At present we are unable to account adequately for this observation, and further studies are underway to explain these results
    • 1H NMR analysis of the crude reaction mixtures). At present we are unable to account adequately for this observation, and further studies are underway to explain these results.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.