Heterogeneity of angiogenic activity in a human liposarcoma: A proposed mechanism for "no take" of human tumors in mice

Journal of the National Cancer Institute

Volumn 93, Issue 14, 2001, Pages 1075-1081

  Achilles, Eike Gert ^a,b   Fernandez, Antonio ^a   Allred, Elizabeth N ^c,d   Kisker, Oliver ^d,e   Udagawa, Taturo ^a   Beecken, Wolf Dietrich ^d,f   Flynn, Evelyn ^a   Folkman, Judah ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c Children's Hospital   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e UNIVERSITY HOSPITAL MARBURG   (Germany)

^f UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENIC FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER TRANSPLANTATION; CELL ACTIVITY; CELL CLONE; CELL HETEROGENEITY; CELL POPULATION; CELL PROLIFERATION; CELL SUSPENSION; CELL TRANSPLANTATION; CONTROLLED STUDY; CORRELATION FUNCTION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; IN VIVO STUDY; LIPOSARCOMA; METASTASIS; MICROVASCULATURE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REGULATORY MECHANISM; SCID MOUSE; STATISTICAL ANALYSIS; TRANSGENIC MOUSE; TUMOR CELL LINE; TUMOR GROWTH; TUMOR RECURRENCE; TUMOR VOLUME; TUMOR XENOGRAFT; XENOTRANSPLANTATION;

EID: 0035908492     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/93.14.1075     Document Type: Article

References (33)

1. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
2. Regulation of the activity of a new inhibitor of angiogenesis by a cancer suppressor gene
3. Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma
4. Angiogenesis in breast cancer
5. Tumor angiogenesis
6. Tumoral vascularity as a prognostic factor in cancer
7. Induction of angiogenesis during the transition from hyperplasia to neoplasia
8. Transplantation of human tumors in nude mice
9. One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice
10. Heterotransplantation of human cancers into nude mice: A model system for human cancer
11. Growth pattern and differentiation of human soft tissue sarcomas in nude mice
12. Regional differences in the growth of normal and neoplastic cells
13. Interferons α and β down-regulate the expression of basic fibroblast growth factor in human carcinomas
14. Genetic heterogeneity of angiogenesis in mice
15. Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression
16. Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
17. The use of the rank transform in regression
18. The rise and fall of apoptosis during multistage tumorigenesis: Down-modulation contributes to tumor progression from angiogenic progenitors
19. Spontaneous apoptosis is inversely related to intratumoral microvessel density in gastric carcinoma
20. Thrombospondin-2: A potent endogenous inhibitor of tumor growth and angiogenesis
21. Implication of cell kinetic changes during the progression of human prostatic cancer
22. Tumor progression in nude mice and its representation in cell culture
23. Heterogeneity in the production of collagens and fibronectin by morphologically distinct clones of a human tumor cell line: Evidence for intrasmoral diversity in matrix protein biosynthesis
24. Heterogeneous regional expression patterns of matrix metalloproteinases in human malignant gliomas
25. Intratumoral heterogeneity and inverse correlation between expression of E-cadherin and collagenase type IV in human gastric carcinomas
26. Relative expression of type IV collagenase, E-cadherin, and vascular endothelial growth factor/vascular permeability factor in prostatectomy specimens distinguishes organ-confined from pathologically advanced prostate cancers
27. Tumor angiogenesis activity of human choriocarcinoma cells grown in vitro
28. Natural history of breast cancer. Progression from hyperplasia to neoplasia as predicted by angiogenesis
29. Breast cancer and atypia among young and middle-aged women: A study of 110 medicolegal autopsies
30. Occult papillary carcinoma of the thyroid. A "normal" finding in Finland. A systematic autopsy study
31. Adenocarcinoma of the prostate in cystoprostastectomy specimens removed for bladder cancer
32. Perspective: Tumour spread--the problems of latency