Behavioral effects of agents active at the γ-aminobutyric acid receptor complex in the staircase paradigm

Brain Research

Volumn 901, Issue 1-2, 2001, Pages 137-142

  Weizman, Ronit ^a,b   Paz, Lior ^b   Peter, Yakov ^b   Toren, Paz ^a,b   Pick, Chaim G ^b  

^a TEL AVIV COMMUNITY MENTAL HEALTH CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

Clonazepam; Dehydroepiandrosterone; Dehydroepiandrosterone sulfate; Flumazenil; GABAA receptor complex; Gabapentin; Staircase test; Zopiclone

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; ANTICONVULSIVE AGENT; BENZODIAZEPINE RECEPTOR BLOCKING AGENT; BENZODIAZEPINE RECEPTOR STIMULATING AGENT; CLONAZEPAM; FLUMAZENIL; GABAPENTIN; HYPNOTIC AGENT; PRASTERONE; PRASTERONE SULFATE; ZOPICLONE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CLIMBING; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; DRUG RECEPTOR BINDING; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REARING; TRANQUILIZING ACTIVITY;

ACETIC ACIDS; ADJUVANTS, IMMUNOLOGIC; AMINES; ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY; BEHAVIOR, ANIMAL; BRAIN; CLONAZEPAM; CYCLOHEXANECARBOXYLIC ACIDS; DEHYDROEPIANDROSTERONE; DEHYDROEPIANDROSTERONE SULFATE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXPLORATORY BEHAVIOR; FLUMAZENIL; GABA MODULATORS; GAMMA-AMINOBUTYRIC ACID; HYPNOTICS AND SEDATIVES; MALE; MICE; MICE, INBRED ICR; MOTOR ACTIVITY; NEURONS; PIPERAZINES; RECEPTORS, GABA-A;

EID: 0035906524     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)02331-9     Document Type: Article

References (11)

1. Benzodiazepine antagonist RO 15-1788 partly reverses some anxiolytic effects of ethanol in the mouse
2. Effects of benzodiazepine agonist, inverse agonist and antagonist drugs in the mouse staircase test
3. Alprazolam increases dehydroepiandrosterone concentrations
4. Pregnenolone and pregnenolone sulfate, alone and with ethanol, in mice on the plus-maze
5. Characterization of steroid interactions with γ-aminobutyric acid receptor-gated chloride channels: Evidence for multiple steroid recognition sites
6. Effect of the pregnane-related GABA-active steroid alphaxlone on mice performance in the staircase test
7. Effect of the neuroactive steroid α-THDOC on staircase test behavior in mice
8. The staircase test: Some evidence of nonspecificity for anxiolytics
9. The staircase test in mice: A simple and efficient procedure for primary screening of anxiolytic agents
10. Comparing benzodiazepines using the staircase test in mice
11. Mouse strains differ in their sensitivity to alprazolam effect in the staircase test