Synthesis of tricyclic azakynurenic acids as a new class of NMDA-glycine antagonists using novel stille coupling reaction

Synlett

Volumn , Issue SPEC. ISS., 1997, Pages 473-474

  Hume, W Ewan ^a   Nagata, Ryu ^a  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001733153     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1997-6149     Document Type: Article

References (19)

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14. 3) δ 8.47 (s, 1H), 8.11 (d, 1 H, J = 2 Hz), 7.76 (d, 2 H, J = 8.2 Hz), 7.28 (d, 2 H, J = 8.2 Hz), 7.24 (d, 1 H, J = 2 Hz), 4.19 (t, 2 H, J = 6 Hz), 4.08 (s, 3 H), 3.10 (t, 2 H, J = 6 Hz), 2.39 (s, 3H).
15. (a) Krolski, M. E.; Renaldo, A. F.; Rudisill, D. E.; Stille, J. K. J. Org. Chem. 1988, 53, 1170.
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18. 6) δ 10.16 (bs, 1 H), 8.05 (d, 1 H, J = 2 Hz), 7.55 (d, 1 H, J = 2 Hz), 7.25 (s, 1 H), 3.92 - 4.04 (m, 1 H), 3.30 (dd, 1 H, J = 18, 5.4 Hz), 2.95 (dd, 1 H, J = 18, 10 Hz), 1.36 (d, 3 H, J = 7.2 Hz).
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